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- W973204234 abstract "The interaction of metal complex with RNA has been studied by isothermal titration calorimetry (ITC) for the first time. ITC experiments show that complex [Ru(phen)2MPIP]^2+ {phen= 1,10-phenanthroline, MP[P-2-(4-methylphenyl)imidazo[4,5-f]-1, 10-phenanthroline} interacts with yeast tRNA in terms of a model for a singleset of identical sites through intercalation, which is consistent with our previous observation obtained from spectroscopic methods, and this binding process was driven by a moderately favorable enthalpy decrease in combination with a moderately favorable entropy increase, suggesting that ITC is an effective method for deep studying the interactions of metal complexes with RNA." @default.
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- W973204234 date "2005-01-01" @default.
- W973204234 modified "2023-09-23" @default.
- W973204234 title "Interaction of Ru（II） Complex with Yeast tRNA Studied by Isothermal Titration Calorimetry" @default.
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