FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W974235669> ?p ?o ?g. }

• W974235669 abstract "Abstract The response to treatment and overall survival of patients with AML is heterogeneous. Prognostic factors are urgently needed in order to be able to better predict treatment outcomes. The aim of the present work was to study telomere length and human telomerase reverse transcriptase (hTERT) level in acute myeloid leukemia and to detect if these parameters might be useful in providing insight into the clinical outcome of AML patients. ELISA technique was used to measure hTERT level quantitative PCR for measuring telomere length. The study included 70 individuals, 50 patients with acute myeloid leukemia and twenty healthy individuals with comparable age and sex. There was statistically significant higher level of hTERT and lower RTL in patients than controls. The patients were treated according to the standard chemotherapy protocol for induction and they were followed up by bone marrow examination. Mean hTERT level in patients who did not achieve complete hematological remission was statistically significant higher than that in patients who achieved complete hematological remission (48.87 and 34.32 respectively) (z = −1.98, p = 0.048). Mean RTL in patients who achieved remission was higher than that in patients who did not achieve remission (0.56 and 0.37 respectively). However, it did not reach statistical significance. Median survival time in patients who achieved remission was statistically significant longer than that in those who did not achieve remission (26 ms and 4 ms respectively). It was found that both relative telomere length and hTERT could be used for assessing clinical behavior and predicting treatment outcome in AML patients." @default.
• W974235669 created "2016-06-24" @default.
• W974235669 creator A5020363581 @default.
• W974235669 creator A5029635438 @default.
• W974235669 creator A5040972187 @default.
• W974235669 creator A5052917430 @default.
• W974235669 creator A5067352887 @default.
• W974235669 date "2015-09-01" @default.
• W974235669 modified "2023-09-27" @default.
• W974235669 title "Telomere length and human telomerase reverse transcriptase (hTERT) level in patients with acute myeloid leukemia: Impact on clinical outcome" @default.
• W974235669 cites W1910707300 @default.
• W974235669 cites W1966028695 @default.
• W974235669 cites W1987845056 @default.
• W974235669 cites W1990046380 @default.
• W974235669 cites W1993198796 @default.
• W974235669 cites W1996448587 @default.
• W974235669 cites W1999551057 @default.
• W974235669 cites W1999688002 @default.
• W974235669 cites W2002555927 @default.
• W974235669 cites W2003708416 @default.
• W974235669 cites W2010074913 @default.
• W974235669 cites W2031637280 @default.
• W974235669 cites W2036478371 @default.
• W974235669 cites W2079918825 @default.
• W974235669 cites W2087145217 @default.
• W974235669 cites W2104134670 @default.
• W974235669 cites W2106534122 @default.
• W974235669 cites W2125161023 @default.
• W974235669 cites W2129632994 @default.
• W974235669 cites W2132139555 @default.
• W974235669 cites W2133650635 @default.
• W974235669 cites W2139801283 @default.
• W974235669 cites W2142416341 @default.
• W974235669 cites W2160621707 @default.
• W974235669 cites W2165903785 @default.
• W974235669 cites W4254759378 @default.
• W974235669 cites W60903004 @default.
• W974235669 doi "https://doi.org/10.1016/j.achaem.2015.07.003" @default.
• W974235669 hasPublicationYear "2015" @default.
• W974235669 type Work @default.
• W974235669 sameAs 974235669 @default.
• W974235669 citedByCount "1" @default.
• W974235669 countsByYear W9742356692019 @default.
• W974235669 crossrefType "journal-article" @default.
• W974235669 hasAuthorship W974235669A5020363581 @default.
• W974235669 hasAuthorship W974235669A5029635438 @default.
• W974235669 hasAuthorship W974235669A5040972187 @default.
• W974235669 hasAuthorship W974235669A5052917430 @default.
• W974235669 hasAuthorship W974235669A5067352887 @default.
• W974235669 hasConcept C104317684 @default.
• W974235669 hasConcept C125593758 @default.
• W974235669 hasConcept C126322002 @default.
• W974235669 hasConcept C143998085 @default.
• W974235669 hasConcept C146357865 @default.
• W974235669 hasConcept C151730666 @default.
• W974235669 hasConcept C156719811 @default.
• W974235669 hasConcept C177336024 @default.
• W974235669 hasConcept C203014093 @default.
• W974235669 hasConcept C2776694085 @default.
• W974235669 hasConcept C2778461978 @default.
• W974235669 hasConcept C2778729363 @default.
• W974235669 hasConcept C3018657049 @default.
• W974235669 hasConcept C49105822 @default.
• W974235669 hasConcept C55493867 @default.
• W974235669 hasConcept C63363279 @default.
• W974235669 hasConcept C71924100 @default.
• W974235669 hasConcept C86803240 @default.
• W974235669 hasConcept C90924648 @default.
• W974235669 hasConcept C94581717 @default.
• W974235669 hasConceptScore W974235669C104317684 @default.
• W974235669 hasConceptScore W974235669C125593758 @default.
• W974235669 hasConceptScore W974235669C126322002 @default.
• W974235669 hasConceptScore W974235669C143998085 @default.
• W974235669 hasConceptScore W974235669C146357865 @default.
• W974235669 hasConceptScore W974235669C151730666 @default.
• W974235669 hasConceptScore W974235669C156719811 @default.
• W974235669 hasConceptScore W974235669C177336024 @default.
• W974235669 hasConceptScore W974235669C203014093 @default.
• W974235669 hasConceptScore W974235669C2776694085 @default.
• W974235669 hasConceptScore W974235669C2778461978 @default.
• W974235669 hasConceptScore W974235669C2778729363 @default.
• W974235669 hasConceptScore W974235669C3018657049 @default.
• W974235669 hasConceptScore W974235669C49105822 @default.
• W974235669 hasConceptScore W974235669C55493867 @default.
• W974235669 hasConceptScore W974235669C63363279 @default.
• W974235669 hasConceptScore W974235669C71924100 @default.
• W974235669 hasConceptScore W974235669C86803240 @default.
• W974235669 hasConceptScore W974235669C90924648 @default.
• W974235669 hasConceptScore W974235669C94581717 @default.
• W974235669 hasLocation W9742356691 @default.
• W974235669 hasOpenAccess W974235669 @default.
• W974235669 hasPrimaryLocation W9742356691 @default.
• W974235669 hasRelatedWork W133367521 @default.
• W974235669 hasRelatedWork W1982475127 @default.
• W974235669 hasRelatedWork W2002090421 @default.
• W974235669 hasRelatedWork W2050400868 @default.
• W974235669 hasRelatedWork W2315471426 @default.
• W974235669 hasRelatedWork W2347776228 @default.
• W974235669 hasRelatedWork W2361888538 @default.
• W974235669 hasRelatedWork W2374081209 @default.

• next