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- W974407462 abstract "Scents are the primary means of communication in mice. They underlie most aspects of their social behaviour and are particularly important in mediating aggressive interactions and status differentiation among males. This competitive aggression can be a major welfare concern and source of uncontrolled variation among laboratory mice. Scents also play an invisible role in priming reproductive physiology and development with additional consequences for immunocompetence, introducing another potential source of uncontrolled variation that could influence many types of experiment. Here, I provide a brief explanation of how wild mice use scents to recognise each other and to control competitive interactions. I then discuss the consequences of this for aggression among laboratory mice and recommend ways to minimize problems through management practices. Known reproductive priming effects are also summarised to show how exposure to scents and cage group size can influence sex hormone levels, reproductive cycling and development. Careful consideration of husbandry and experimental design can also reduce this source of variability." @default.
- W974407462 created "2016-06-24" @default.
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- W974407462 date "2005-01-01" @default.
- W974407462 modified "2023-09-26" @default.
- W974407462 title "Making sense of scents: reducing aggression and uncontrolled variation in laboratory mice" @default.
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