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- W97473078 abstract "Defensive rage behavior – a naturally occurring behavior elicited in the presence of a threatening stimulus – is characterized mostly in felines by hissing, arching of the back, retraction of its ears, piloerection, and forelimb striking of the object perceived to be a threat. This form of aggression bears close similarities to that seen in several classes of psychiatric disorders such as in schizophrenia and borderline personality disorder in the human patient as well as in nonpatient displays of aggression such as ‘road rage.’ In the cat, defensive rage can be elicited by electrical stimulation of the medial hypothalamus or midbrain periaqueductal gray (PAG) and is modulated by limbic structures. The primary descending pathway from the medial hypothalamus for the expression of defensive rage projects to the PAG. The functions of monoamine, amino acid, and peptide neurotransmitters regulating defensive rage have been identified as well as cytokines within the hypothalamus and PAG, which also powerfully regulate defensive rage behavior." @default.
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- W97473078 date "2010-01-01" @default.
- W97473078 modified "2023-09-27" @default.
- W97473078 title "Neural Bases of Defensive Aggression" @default.
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- W97473078 doi "https://doi.org/10.1016/b978-0-08-045396-5.00084-1" @default.
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