Matches in SemOpenAlex for { <https://semopenalex.org/work/W976071720> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W976071720 endingPage "721" @default.
- W976071720 startingPage "715" @default.
- W976071720 abstract "One hundred and sixty-eight different specimens of human carcinoma of the lung were tested for in vitro drug sensitivity using the human tumor clonogenic assay (HTCA) originally described by Hamburger and Salmon. One hundred and twenty-two (73%) specimens grew adequately for chemosensitivity testing. Most tumors were resistant to chemotherapeutic drugs, but in vitro sensitivity, regardless of the type of drugs, varied markedly from specimen to specimen. Although response rates to individual drugs ranged between 9% and 23%, half the specimens tested were sensitive in vitro to at least one drug. A higher in vitro sensitivity rate was observed in small cell lung carcinoma (31%) than in non-small cell lung carcinoma (17%). The frequency of in vitro sensitivity was greater for patients who had received no prior chemotherapy than those who were in relapse. These in vitro results are similar to current clinical experience. There was a significant association between in vitro sensitivity of cells from a primary tumor as compared to its metastases. Overall HTCA appears to be useful in selecting appropriate chemotherapy for individual patients with carcinoma of the lung." @default.
- W976071720 created "2016-06-24" @default.
- W976071720 creator A5022085173 @default.
- W976071720 creator A5034855620 @default.
- W976071720 creator A5044442302 @default.
- W976071720 creator A5047834232 @default.
- W976071720 creator A5053435376 @default.
- W976071720 creator A5058549884 @default.
- W976071720 creator A5058620859 @default.
- W976071720 creator A5063730392 @default.
- W976071720 creator A5069283963 @default.
- W976071720 creator A5076349434 @default.
- W976071720 date "1986-09-01" @default.
- W976071720 modified "2023-09-26" @default.
- W976071720 title "IN VITRO CHEMOSENSITIVITY PATTERNS OF CARCINOMA OF THE LUNG IN HUMAN TUMOR CLONOGENIC ASSAY" @default.
- W976071720 hasPublicationYear "1986" @default.
- W976071720 type Work @default.
- W976071720 sameAs 976071720 @default.
- W976071720 citedByCount "0" @default.
- W976071720 crossrefType "journal-article" @default.
- W976071720 hasAuthorship W976071720A5022085173 @default.
- W976071720 hasAuthorship W976071720A5034855620 @default.
- W976071720 hasAuthorship W976071720A5044442302 @default.
- W976071720 hasAuthorship W976071720A5047834232 @default.
- W976071720 hasAuthorship W976071720A5053435376 @default.
- W976071720 hasAuthorship W976071720A5058549884 @default.
- W976071720 hasAuthorship W976071720A5058620859 @default.
- W976071720 hasAuthorship W976071720A5063730392 @default.
- W976071720 hasAuthorship W976071720A5069283963 @default.
- W976071720 hasAuthorship W976071720A5076349434 @default.
- W976071720 hasConcept C117262875 @default.
- W976071720 hasConcept C121608353 @default.
- W976071720 hasConcept C126322002 @default.
- W976071720 hasConcept C142724271 @default.
- W976071720 hasConcept C143998085 @default.
- W976071720 hasConcept C202751555 @default.
- W976071720 hasConcept C2776694085 @default.
- W976071720 hasConcept C2777546739 @default.
- W976071720 hasConcept C2777714996 @default.
- W976071720 hasConcept C2778076430 @default.
- W976071720 hasConcept C2779292878 @default.
- W976071720 hasConcept C2781182431 @default.
- W976071720 hasConcept C502942594 @default.
- W976071720 hasConcept C55493867 @default.
- W976071720 hasConcept C71924100 @default.
- W976071720 hasConcept C86803240 @default.
- W976071720 hasConceptScore W976071720C117262875 @default.
- W976071720 hasConceptScore W976071720C121608353 @default.
- W976071720 hasConceptScore W976071720C126322002 @default.
- W976071720 hasConceptScore W976071720C142724271 @default.
- W976071720 hasConceptScore W976071720C143998085 @default.
- W976071720 hasConceptScore W976071720C202751555 @default.
- W976071720 hasConceptScore W976071720C2776694085 @default.
- W976071720 hasConceptScore W976071720C2777546739 @default.
- W976071720 hasConceptScore W976071720C2777714996 @default.
- W976071720 hasConceptScore W976071720C2778076430 @default.
- W976071720 hasConceptScore W976071720C2779292878 @default.
- W976071720 hasConceptScore W976071720C2781182431 @default.
- W976071720 hasConceptScore W976071720C502942594 @default.
- W976071720 hasConceptScore W976071720C55493867 @default.
- W976071720 hasConceptScore W976071720C71924100 @default.
- W976071720 hasConceptScore W976071720C86803240 @default.
- W976071720 hasIssue "9" @default.
- W976071720 hasLocation W9760717201 @default.
- W976071720 hasOpenAccess W976071720 @default.
- W976071720 hasPrimaryLocation W9760717201 @default.
- W976071720 hasRelatedWork W1980427312 @default.
- W976071720 hasRelatedWork W2000832011 @default.
- W976071720 hasRelatedWork W2013399673 @default.
- W976071720 hasRelatedWork W2052837225 @default.
- W976071720 hasRelatedWork W2092156894 @default.
- W976071720 hasRelatedWork W2103533511 @default.
- W976071720 hasRelatedWork W2147453919 @default.
- W976071720 hasRelatedWork W2281099157 @default.
- W976071720 hasRelatedWork W2283321152 @default.
- W976071720 hasRelatedWork W2321267167 @default.
- W976071720 hasRelatedWork W2333364158 @default.
- W976071720 hasRelatedWork W2368884447 @default.
- W976071720 hasRelatedWork W2382301707 @default.
- W976071720 hasRelatedWork W2401088697 @default.
- W976071720 hasRelatedWork W2412499000 @default.
- W976071720 hasRelatedWork W2414722877 @default.
- W976071720 hasRelatedWork W2418154417 @default.
- W976071720 hasRelatedWork W2438928942 @default.
- W976071720 hasRelatedWork W422409661 @default.
- W976071720 hasRelatedWork W190200617 @default.
- W976071720 hasVolume "9" @default.
- W976071720 isParatext "false" @default.
- W976071720 isRetracted "false" @default.
- W976071720 magId "976071720" @default.
- W976071720 workType "article" @default.