Matches in SemOpenAlex for { <https://semopenalex.org/work/W977070993> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W977070993 abstract "Background: Adverse neurocognitive outcome has been a continuing challenge to modern cardiac surgery. Cardiac valve replacement implies a high risk of neuronal injury. However, long-term studies of cognitive function do not exist until now. We aimed to assess the course of cognitive performance during 3 years after cardiac valve surgery and to identify factors that may predict long-term outcome. Methods: A total of 30 patients (64.9±9.8 yrs.) undergoing elective isolated heart valve replacement as the first time cardiac operation were prospectively investigated preoperatively, at discharge, 3 months and 3 years after surgery. Neuropsychological performance was evaluated with a battery of 11 standardized psychometric tests measuring seven cognitive domains (psychomotor speed, executive function, attention, verbal memory, visual memory, logical thinking, visuoconstruction). High-resolution multi-sequence magnetic resonance imaging (MRI) including diffusion-weighted technique was performed to detect cerebral ischemia. Results: Cognitive deficits (drop of ≥1 standard deviation in scores in ≥3 tests) were present in 15/30 patients (50%) at discharge, 2/30 patients (7%) at 3 months, and 4/25 patients (16%) at 3 years compared to baseline, respectively. Both patients with a deficit at 3 months behaved normal at discharge, and none of the patients had a persistent deficit. Postoperative MRI disclosed 41 new focal ischemic brain lesions in 47% of patients (1–7 lesions/patient; lesion volume 91–745 mm 3 ). All lesions were neurologically silent. None of the variables tested by stepwise regression analyses including medical history data, operative factors, preexisting or new postoperative ischemic lesions on MRI, postoperative adverse events or type of prosthesis were found to predict late cognitive decline. Conclusions: Cognitive decline after cardiac valve replacement is benign and frequently resolves within weeks. The few cognitive deficits that were found years later are most likely related to factors other than the operation itself." @default.
- W977070993 created "2016-06-24" @default.
- W977070993 creator A5008547523 @default.
- W977070993 creator A5021280001 @default.
- W977070993 creator A5022948027 @default.
- W977070993 creator A5026525345 @default.
- W977070993 creator A5035620570 @default.
- W977070993 creator A5059940550 @default.
- W977070993 creator A5079084775 @default.
- W977070993 creator A5087456689 @default.
- W977070993 date "2007-10-16" @default.
- W977070993 modified "2023-09-27" @default.
- W977070993 title "Abstract 2063: Longitudinal Follow-up Of Cognitive Function After Cardiac Valve Replacement: A Three-Year Prospective Study" @default.
- W977070993 doi "https://doi.org/10.1161/circ.116.suppl_16.ii_447" @default.
- W977070993 hasPublicationYear "2007" @default.
- W977070993 type Work @default.
- W977070993 sameAs 977070993 @default.
- W977070993 citedByCount "0" @default.
- W977070993 crossrefType "journal-article" @default.
- W977070993 hasAuthorship W977070993A5008547523 @default.
- W977070993 hasAuthorship W977070993A5021280001 @default.
- W977070993 hasAuthorship W977070993A5022948027 @default.
- W977070993 hasAuthorship W977070993A5026525345 @default.
- W977070993 hasAuthorship W977070993A5035620570 @default.
- W977070993 hasAuthorship W977070993A5059940550 @default.
- W977070993 hasAuthorship W977070993A5079084775 @default.
- W977070993 hasAuthorship W977070993A5087456689 @default.
- W977070993 hasConcept C105641010 @default.
- W977070993 hasConcept C118552586 @default.
- W977070993 hasConcept C126838900 @default.
- W977070993 hasConcept C141071460 @default.
- W977070993 hasConcept C14216870 @default.
- W977070993 hasConcept C143409427 @default.
- W977070993 hasConcept C164705383 @default.
- W977070993 hasConcept C169900460 @default.
- W977070993 hasConcept C172467417 @default.
- W977070993 hasConcept C2776570981 @default.
- W977070993 hasConcept C2778921608 @default.
- W977070993 hasConcept C2780007028 @default.
- W977070993 hasConcept C2780026749 @default.
- W977070993 hasConcept C71924100 @default.
- W977070993 hasConceptScore W977070993C105641010 @default.
- W977070993 hasConceptScore W977070993C118552586 @default.
- W977070993 hasConceptScore W977070993C126838900 @default.
- W977070993 hasConceptScore W977070993C141071460 @default.
- W977070993 hasConceptScore W977070993C14216870 @default.
- W977070993 hasConceptScore W977070993C143409427 @default.
- W977070993 hasConceptScore W977070993C164705383 @default.
- W977070993 hasConceptScore W977070993C169900460 @default.
- W977070993 hasConceptScore W977070993C172467417 @default.
- W977070993 hasConceptScore W977070993C2776570981 @default.
- W977070993 hasConceptScore W977070993C2778921608 @default.
- W977070993 hasConceptScore W977070993C2780007028 @default.
- W977070993 hasConceptScore W977070993C2780026749 @default.
- W977070993 hasConceptScore W977070993C71924100 @default.
- W977070993 hasIssue "suppl_16" @default.
- W977070993 hasLocation W9770709931 @default.
- W977070993 hasOpenAccess W977070993 @default.
- W977070993 hasPrimaryLocation W9770709931 @default.
- W977070993 hasRelatedWork W1965737851 @default.
- W977070993 hasRelatedWork W2002690030 @default.
- W977070993 hasRelatedWork W2015873403 @default.
- W977070993 hasRelatedWork W2041944042 @default.
- W977070993 hasRelatedWork W2132469427 @default.
- W977070993 hasRelatedWork W2354457233 @default.
- W977070993 hasRelatedWork W2369535500 @default.
- W977070993 hasRelatedWork W2391674521 @default.
- W977070993 hasRelatedWork W2462155031 @default.
- W977070993 hasRelatedWork W563435607 @default.
- W977070993 hasVolume "116" @default.
- W977070993 isParatext "false" @default.
- W977070993 isRetracted "false" @default.
- W977070993 magId "977070993" @default.
- W977070993 workType "article" @default.