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- W977961878 abstract "Quantitative free amino acid levels of amniotic fluid, maternal and fetal sera, and fetal urine were determined in 9 early pregnancies. Statistical analysis indicated a positive correlation between amino acid levels in amniotic fluid with those in fetal serum and urine. These data suggest an exchange mechanism between amniotic fluid and fetal serum, in addition to placental exchange, with fetal urine acting as a diluent of amniotic fluid. Analogue studies in 2 pregnancies indicate a high turnover of amino acids in maternal serum with a slower rate in amniotic fluid (t½ = 8 ± 1 days). It is postulated that genetic disorders which result in high concentrations of metabolites in fetal serum could be detected by amniotic fluid analysis." @default.
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- W977961878 date "1973-07-01" @default.
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- W977961878 title "The free amino acids in maternal and fetal extracellular fluids collected during early pregnancy" @default.
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- W977961878 doi "https://doi.org/10.1016/0002-9378(73)91021-1" @default.
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