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- W977985359 abstract "Dietary and nutritional factors are widely recognized to be important factors in the genesis of human cancer (1–4). The possible mechanisms involved have been discussed in several review articles (5–7). The high incidence of gastrointestinal cancers in many Third World countries is correlated with the presence of carcinogens, such as aflatoxin and nitrosamines, in the diet (8–10) as well as nutritional deficiencies which are believed to enhance carcinogenesis (7,11). For example, a higher risk for gastric cancer has been shown to be associated with infrequent consumption of fruits and vegetables (3,12–15). Similarly, a high incidence of esophageal cancer is frequently found among individuals who consume low levels of vegetables and fruits and with low plasma levels of vitamins C and E as well as other micronutrients. This chapter explores the possible mechanisms by which constituents in vegetables and fruits inhibit carcinogenesis by blocking the endogenous synthesis of carcinogenic N-nitroso compounds. The etiology of esophageal cancer in Linxian, China is discussed in detail to substantiate this possibility." @default.
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- W977985359 date "1990-01-01" @default.
- W977985359 modified "2023-10-14" @default.
- W977985359 title "Effect of Nutrition on Carcinogenesis: Mechanisms Involving Nitrosamines" @default.
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- W977985359 doi "https://doi.org/10.1007/978-1-4612-4516-2_4" @default.
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