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- W980312946 abstract "The analysis of short-chain fatty acids [volatile fatty acids; acetic acid (C3)-caproic acid (C6)] is found useful in the clinical and biological application of the relationship between coma from liver failure and lipid metabolism disorder. The determination of long-chain fatty acids [up to lauric acid (C12)] is of importance in the relationship between lipid metabolism and adult health. In particular, long-chain mono and polyunsaturated fatty acids lead to ATP by β-oxidation, and, together with phospholipids, cholesterol and neutral lipids, are the component elements in cell membranes. Hence, these fatty acids relate to many important physiological roles, such as transportation and oxidative phosphorylation. This chapter describes the De novo synthesis of saturated fatty acids. Acetyl-CoA, a biotin-containing enzyme produced in the mitochondria, is the substrate for acetyl-CoA carboxylase. This enzyme first forms the N-carboxybiotin complex, a reaction requiring ATP. Subsequently, the carboxy group is transferred to acetyl-CoA to form malonyl-CoA." @default.
- W980312946 created "2016-06-24" @default.
- W980312946 creator A5003458566 @default.
- W980312946 date "1991-01-01" @default.
- W980312946 modified "2023-09-25" @default.
- W980312946 title "Chapter 7 Fatty Acids" @default.
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- W980312946 doi "https://doi.org/10.1016/s0301-4770(08)60287-0" @default.
- W980312946 hasPublicationYear "1991" @default.
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