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- W982092013 abstract "Three groups of non-camptothecin compounds with four to five fused rings have been designed and synthesized. Their in vitro anti-proliferative activity has been evaluated with five different cancer cell lines (HCT116, PC3, U87MG, HepG2, SK-OV-3). Compounds B-2 and B-3 showed the most potent cell growth inhibition with IC50 of 169 nM and 325 nM against U87MG cell line correspondingly." @default.
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- W982092013 date "2015-10-01" @default.
- W982092013 modified "2023-10-16" @default.
- W982092013 title "Design, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors" @default.
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- W982092013 doi "https://doi.org/10.1016/j.bmcl.2015.06.042" @default.
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