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- W982244103 abstract "目的：探讨癌胚抗原(CEA)、细胞角蛋白19片段(CYFRA21-1)、神经特异性烯醇化酶(NSE)、癌抗原72-4(CA724)联合检测对肺癌的诊断价值。方法：采用电化学发光法检测56例肺癌(腺癌组24例，鳞癌组20例，小细胞肺癌组12例)、34例肺部良性疾病(良性疾病组)、30名健康人(对照组)血清CEA、CYFRA21-1、NSE、CA724水平并进行分析。结果：5组血清CEA、CYFRA21-1、NSE和CA724水平差异均有统计学意义(P0.01)。腺癌组CEA、鳞癌组CYFRA21-1和小细胞肺癌组NSE均明显高于相应其他4组(P0.01)。腺癌组CA724均明显高于对照组和良性疾病组(P0.01)。腺癌组CEA、鳞癌组CYFRA21-1、小细胞肺癌组NSE和腺癌组CA724阳性率均高于对照组和良性疾病组(P0.05~P0.01) 。4种标志物单项检测时，特异性为88.9%~94.4%，敏感性为28.6%~41.1%。联合检测后，特异性略下降(83.3%)，但敏感性明显提高(87.5%)。结论：血清CEA、CYFRA21-1、NSE、CA724水平和肺癌的病理分型有一定的相关性，其联合检测可提高对肺癌的阳性检出率。" @default.
- W982244103 created "2016-06-24" @default.
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- W982244103 date "2014-04-15" @default.
- W982244103 modified "2023-10-18" @default.
- W982244103 title "血清CEA、CYFRA21-1、NSE、CA724联合检测对肺癌的诊断价值" @default.
- W982244103 hasPublicationYear "2014" @default.
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