Matches in SemOpenAlex for { <https://semopenalex.org/work/W982542403> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W982542403 endingPage "213" @default.
- W982542403 startingPage "208" @default.
- W982542403 abstract "We previously reported that Wistar Kyoto rats, an animal model of depression, have a characteristically abnormal serine metabolism in the brain, i.e., lower serine and cystathionine, which is a metabolite of serine, concentrations in the brain. To explore the mechanism underlying this abnormality, the expression of cystathionine β-synthase and serine racemase, which are the enzymes involved in the serine metabolism, was investigated in the cerebellum and hippocampus of Wistar and Wistar Kyoto rats. Wistar Kyoto rats exhibited a significantly lower mRNA expression of cystathionine β-synthase in the cerebellum in comparison with Wistar rats, while expression levels in the hippocampus did not differ between strains. Previous study indicated that the reduction of cystathionine β-synthase in the brain induced cerebellar aplasia in mice. Therefore, the cerebellar size was compared between Wistar rats and Wistar Kyoto rats. Wistar Kyoto rats displayed a lower ratio of cerebellum weight to whole-brain weight compared with Wistar rats of the same generation or similar body weight, suggesting that Wistar Kyoto rats exhibit smaller cerebellum. These results suggest that the lower mRNA expression of cystathionine β-synthase in the cerebellum and the smaller size of cerebellum may be related to the depression-like behavior in Wistar Kyoto rats." @default.
- W982542403 created "2016-06-24" @default.
- W982542403 creator A5004597787 @default.
- W982542403 creator A5011987568 @default.
- W982542403 creator A5040522826 @default.
- W982542403 creator A5053645131 @default.
- W982542403 creator A5061519603 @default.
- W982542403 creator A5085199471 @default.
- W982542403 date "2015-10-01" @default.
- W982542403 modified "2023-09-27" @default.
- W982542403 title "Suppressed expression of cystathionine β-synthase and smaller cerebellum in Wistar Kyoto rats" @default.
- W982542403 cites W1481473951 @default.
- W982542403 cites W1978926207 @default.
- W982542403 cites W1980424869 @default.
- W982542403 cites W1982708537 @default.
- W982542403 cites W2013774430 @default.
- W982542403 cites W2016547058 @default.
- W982542403 cites W2018463496 @default.
- W982542403 cites W2036089634 @default.
- W982542403 cites W2039602871 @default.
- W982542403 cites W2044069216 @default.
- W982542403 cites W2055076038 @default.
- W982542403 cites W2055096975 @default.
- W982542403 cites W2059192679 @default.
- W982542403 cites W2062790175 @default.
- W982542403 cites W2063075351 @default.
- W982542403 cites W2074345287 @default.
- W982542403 cites W2074657008 @default.
- W982542403 cites W2086792956 @default.
- W982542403 cites W2094050514 @default.
- W982542403 cites W2141412827 @default.
- W982542403 cites W2141610173 @default.
- W982542403 cites W2149932734 @default.
- W982542403 doi "https://doi.org/10.1016/j.brainres.2015.07.043" @default.
- W982542403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26241765" @default.
- W982542403 hasPublicationYear "2015" @default.
- W982542403 type Work @default.
- W982542403 sameAs 982542403 @default.
- W982542403 citedByCount "5" @default.
- W982542403 countsByYear W9825424032017 @default.
- W982542403 countsByYear W9825424032019 @default.
- W982542403 countsByYear W9825424032020 @default.
- W982542403 countsByYear W9825424032023 @default.
- W982542403 crossrefType "journal-article" @default.
- W982542403 hasAuthorship W982542403A5004597787 @default.
- W982542403 hasAuthorship W982542403A5011987568 @default.
- W982542403 hasAuthorship W982542403A5040522826 @default.
- W982542403 hasAuthorship W982542403A5053645131 @default.
- W982542403 hasAuthorship W982542403A5061519603 @default.
- W982542403 hasAuthorship W982542403A5085199471 @default.
- W982542403 hasConcept C126322002 @default.
- W982542403 hasConcept C134018914 @default.
- W982542403 hasConcept C16525657 @default.
- W982542403 hasConcept C181199279 @default.
- W982542403 hasConcept C185592680 @default.
- W982542403 hasConcept C2776414213 @default.
- W982542403 hasConcept C2779201268 @default.
- W982542403 hasConcept C2779652256 @default.
- W982542403 hasConcept C2781161787 @default.
- W982542403 hasConcept C55493867 @default.
- W982542403 hasConcept C71924100 @default.
- W982542403 hasConcept C86803240 @default.
- W982542403 hasConceptScore W982542403C126322002 @default.
- W982542403 hasConceptScore W982542403C134018914 @default.
- W982542403 hasConceptScore W982542403C16525657 @default.
- W982542403 hasConceptScore W982542403C181199279 @default.
- W982542403 hasConceptScore W982542403C185592680 @default.
- W982542403 hasConceptScore W982542403C2776414213 @default.
- W982542403 hasConceptScore W982542403C2779201268 @default.
- W982542403 hasConceptScore W982542403C2779652256 @default.
- W982542403 hasConceptScore W982542403C2781161787 @default.
- W982542403 hasConceptScore W982542403C55493867 @default.
- W982542403 hasConceptScore W982542403C71924100 @default.
- W982542403 hasConceptScore W982542403C86803240 @default.
- W982542403 hasFunder F4320334764 @default.
- W982542403 hasLocation W9825424031 @default.
- W982542403 hasLocation W9825424032 @default.
- W982542403 hasOpenAccess W982542403 @default.
- W982542403 hasPrimaryLocation W9825424031 @default.
- W982542403 hasRelatedWork W1978555483 @default.
- W982542403 hasRelatedWork W1986497911 @default.
- W982542403 hasRelatedWork W2051942816 @default.
- W982542403 hasRelatedWork W2077816349 @default.
- W982542403 hasRelatedWork W2086013593 @default.
- W982542403 hasRelatedWork W2091008837 @default.
- W982542403 hasRelatedWork W2110497742 @default.
- W982542403 hasRelatedWork W2375813713 @default.
- W982542403 hasRelatedWork W2883728153 @default.
- W982542403 hasRelatedWork W4230873741 @default.
- W982542403 hasVolume "1624" @default.
- W982542403 isParatext "false" @default.
- W982542403 isRetracted "false" @default.
- W982542403 magId "982542403" @default.
- W982542403 workType "article" @default.