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- W98325671 abstract "Demyelinating immune neuropathies represent a heterogeneous spectrum of peripheral neuropathic conditions with presumed autoimmune origin. Sensory, motor, and autonomic nerves can be affected resulting in symptoms such as limb weakness, numbness, tingling, pain, and autonomic dysfunction. The neurological symptoms can be asymmetrically distributed but also frequently follow the stereotype distribution pattern of other neuropathies with glove and stocking-like distribution. Other characteristics, which can be used for distinguishing subtypes, include the disease course (acute, rapid onset vs. slowly progressive), electrophysiological measures, and serum antibodies. In recent years, significant advances have been achieved in elucidating underlying pathomechanisms to gain a deeper insight into the molecular and cellular mechanisms resulting in immune-mediated injury of the peripheral nervous system. In this article, the authors discuss aspects of the pathogenesis of acute and chronic demyelinating neuropathies covering the Guillain–Barre syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), multifocal motor neuropathy (MMN), and polyneuropathy associated with antimyelin-associated glycoprotein (MAG) antibodies." @default.
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- W98325671 date "2014-01-01" @default.
- W98325671 modified "2023-09-23" @default.
- W98325671 title "Immunology of Demyelinating Immune Neuropathies" @default.
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- W98325671 doi "https://doi.org/10.1016/b978-0-12-385157-4.00176-7" @default.
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