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- W98399382 abstract "In this chapter we have summarised the mechanisms through which ionizing radiation kills cancer and normal cells and the strategies useful to increase the curative potential of photon energy. If we consider clinical efficacy and the incidence of side effects visible at the inception of radiotherapy, we are aware of the improvements acquired through the investigation of the cell killing by ionizing radiation. But if we consider the distress resulting from clinical failure of current cancer treatments, we believe that much work still needs to be done. It is likely that in future novel techniques for DNA screening of individual cancers, such as DNA microarray technology, will allow identification of single genetic defects generating apoptosis-resistance in a specific cancer. Physical and medical treatment will be tailored to the specific molecular disorder of the individual case, thereby restoring the sensitivity to apoptosis in cancer cells. Therefore, we are convinced that, never as in this case, the study of cell death will contribute to life and wealth." @default.
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- W98399382 date "2002-01-01" @default.
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- W98399382 title "Apoptosis induced by ionizing radiation. The biological basis of radiosensitivity." @default.
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