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• W984002302 abstract "Аtopic cheilitis is a chronic recurrent inflammation of prolabium that occurs in children with atopic dermatitis. In third of them clinical picture of atopic dermatitis is characterized by a manifestative cheilitis with a chronic recurrent course. In some cases, prolabium inflammatory process is the predominant complaint of children with atopic dermatitis, or it may be the solitary clinical sign. Lips lesions at atopic cheilitis is a stress factor and has a negative impact on all life aspects of children, teenagers and people who care for them. The research objective: to determine the risk factors and to study the clinical characteristics of the atopic cheilitis course in children of all age periods. Materials and methods. There were examined 61 children of different age periods with atopic cheilitis, including 19 children with isolated form and 42 children with symptomatic cheilitis against the background of atopic dermatitis. Children were divided into 4 groups: early years (1-3 years old), first and second childhood (4-7 years old and 8-12 years old, respectively) and adolescence (1316 years old). 65 healthy children of similar age groups comprised the control group. Clinical examination of children with atopic cheilitis included subjective and objective methods. For children older than 7 years severity of atopic dermatitis was determined using the SCORAD index, for children under 7 years of age it was assessed using the EASI index. Intraoral examination was performed using the WHO outline and standard instruments kit. Results and discussion. Among the factors of antenatal and postnatal development the most important prerequisites for atopic cheilitis occurrence are presence of exudative diathesis and early (up to 3 months) supplemental feeding in past history. The risk factors for atopic cheilitis in children are the presence of concomitant diseases such as pathology of the gastrointestinal tract (88.52%), food allergy (85.25%), intestinal dysbacteriosis (90.16%), chronic recurrent herpes of lips (70.49%), disorders of carriage and musculoskeletal system (42.62%), chronic tonsillitis (37.7%). In 65.57% of cases the development of atopic cheilitis began against the background of chronic phase of the child (92.5%) or adolescent (7.5%) forms of atopic dermatitis. Severity of clinical manifestations of atopic cheilitis in children with disseminated form of the disease was not always in accord with the severity of atopic dermatitis: while the inflammatory process of prolabium was strongly pronounced, the skin lesions of another typical localization for atopic dermatitis were minor or moderate. Guiding clinical symptoms of atopic cheilitis are skin lichenification of the mouth angle, lips swelling, branny and scaled desquamation, deep or multiple shallow fissures, different intensity itching. Clinical manifestations of atopic cheilitis isolated form and cheilitis against the background of atopic dermatitis have a single-type character. Detection rate of the major signs of the disease (lichenification of the skin at the mouth angles, prolabium hyperaemia, multiple shallow fissures in the area outside of the prolabium, in the mouth angles and in the Klein area, crusts and excoriation) was not the likely level of statistical significance (p > 0,05). For isolated form of atopic cheilitis there are more typical branny desquamation (84.21%) and exfoliative scales along the line of lips closure (47.37%), and for symptomatic cheilitis against the background of atopic dermatitis the same are the absence of distinct boundary between the skin and prolabium (42.86%), scaled desquamation (33.33%) and lips swelling (57.14%)." @default.
• W984002302 created "2016-06-24" @default.
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• W984002302 date "2014-01-01" @default.
• W984002302 modified "2023-09-24" @default.
• W984002302 title "Клінічні особливості та фактори ризику атопічного хейліту в дітей різного віку" @default.
• W984002302 hasPublicationYear "2014" @default.
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