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- W984030522 abstract "Paragangliomas are unusual neuroendocrine cell tumors arising from paraganglia, of which ACTH-secreting cases in the mediastinum are exremely rare. A 51-year-old woman was admitted for generalized edema and weakness which began 5 months ago. Chest X-ray and CT scan revealed a tumor mass in the anterior mediastinum. The plasma cortisol and ACTH levels were very high. Other sources secreting ACTH, except mediastinal mass, were not found. Surgical excision of mediastinal mass and left supraclavicular lymph node was performed. The postoperative microscopic finding and immunohistochemical staining revealed organoid tumor cell nests (zellballen) and S-100 protein positive sustentacular cells which are characteristics of paraganglioma. This was thus a case of Cushingâs syndrome resulting from ectopic ACTH production in anterior mediastinal paraganglioma." @default.
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- W984030522 date "2000-07-31" @default.
- W984030522 modified "2023-09-27" @default.
- W984030522 title "A Case of Cushing`s Syndrome in ACTH - secreting Mediastinal Paraganglioma" @default.
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- W984030522 doi "https://doi.org/10.3904/kjim.2000.15.2.142" @default.
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