Matches in SemOpenAlex for { <https://semopenalex.org/work/W98492166> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W98492166 endingPage "9" @default.
- W98492166 startingPage "222" @default.
- W98492166 abstract "The normal prenatal development of the human pituitary gland and the gland-supporting sella turcica has recently been investigated. The sella turcica area constitutes a developmental boundary area in the cranial base. Posterior to the area the cranial base has developed close to the notochord, and anterior to the region the cranial base development is dependent chiefly on neural crest cell migrations. In the present study the sella turcica region was analyzed in two fetuses with holoprosencephaly (cyclopia and median cleft) and four fetuses with anencephaly combined with rachischisis in the neck region (GA 16-20 weeks). The sella turcica region was investigated radiologically and histologically. Adenohypohyseal gland tissue was localized by immunohistochemical hormonal marking. In both types of malformation an open craniopharyngeal canal was seen in the base of the sella turcica with adenohypophyseal glandular tissue located in the sella turcica, in the canal, and in the pharyngeal connective tissue at the external side of the cranial base. In conclusion, severe malformations of the pituitary gland occur in both holoprosencephaly, which is a polytopic field defect located anterior to the sella turcica, and in anencephaly associated with notochordal insufficiency posterior to the sella turcica. This might indicate that the sella turcica area, bounding different developmental fields, is involved in various craniofacial malformations. It is consequently recommended that examination of the pituitary gland should become a part of the routine autopsy of prenatal material when malformations in the face, brain, and cranial base occur." @default.
- W98492166 created "2016-06-24" @default.
- W98492166 creator A5009586914 @default.
- W98492166 creator A5058562422 @default.
- W98492166 date "1995-10-01" @default.
- W98492166 modified "2023-10-14" @default.
- W98492166 title "Human fetal pituitary gland in holoprosencephaly and anencephaly." @default.
- W98492166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8719351" @default.
- W98492166 hasPublicationYear "1995" @default.
- W98492166 type Work @default.
- W98492166 sameAs 98492166 @default.
- W98492166 citedByCount "9" @default.
- W98492166 countsByYear W984921662016 @default.
- W98492166 countsByYear W984921662018 @default.
- W98492166 countsByYear W984921662022 @default.
- W98492166 countsByYear W984921662023 @default.
- W98492166 crossrefType "journal-article" @default.
- W98492166 hasAuthorship W98492166A5009586914 @default.
- W98492166 hasAuthorship W98492166A5058562422 @default.
- W98492166 hasConcept C105702510 @default.
- W98492166 hasConcept C134018914 @default.
- W98492166 hasConcept C172680121 @default.
- W98492166 hasConcept C2776394550 @default.
- W98492166 hasConcept C2777658017 @default.
- W98492166 hasConcept C2778356730 @default.
- W98492166 hasConcept C2779234561 @default.
- W98492166 hasConcept C2781374659 @default.
- W98492166 hasConcept C54355233 @default.
- W98492166 hasConcept C71315377 @default.
- W98492166 hasConcept C71924100 @default.
- W98492166 hasConcept C86803240 @default.
- W98492166 hasConceptScore W98492166C105702510 @default.
- W98492166 hasConceptScore W98492166C134018914 @default.
- W98492166 hasConceptScore W98492166C172680121 @default.
- W98492166 hasConceptScore W98492166C2776394550 @default.
- W98492166 hasConceptScore W98492166C2777658017 @default.
- W98492166 hasConceptScore W98492166C2778356730 @default.
- W98492166 hasConceptScore W98492166C2779234561 @default.
- W98492166 hasConceptScore W98492166C2781374659 @default.
- W98492166 hasConceptScore W98492166C54355233 @default.
- W98492166 hasConceptScore W98492166C71315377 @default.
- W98492166 hasConceptScore W98492166C71924100 @default.
- W98492166 hasConceptScore W98492166C86803240 @default.
- W98492166 hasIssue "4" @default.
- W98492166 hasLocation W984921661 @default.
- W98492166 hasOpenAccess W98492166 @default.
- W98492166 hasPrimaryLocation W984921661 @default.
- W98492166 hasRelatedWork W1986668456 @default.
- W98492166 hasRelatedWork W2062000751 @default.
- W98492166 hasRelatedWork W2101305986 @default.
- W98492166 hasRelatedWork W2112428174 @default.
- W98492166 hasRelatedWork W2221636810 @default.
- W98492166 hasRelatedWork W26296315 @default.
- W98492166 hasRelatedWork W2811383610 @default.
- W98492166 hasRelatedWork W312832529 @default.
- W98492166 hasRelatedWork W4239874408 @default.
- W98492166 hasRelatedWork W98492166 @default.
- W98492166 hasVolume "15" @default.
- W98492166 isParatext "false" @default.
- W98492166 isRetracted "false" @default.
- W98492166 magId "98492166" @default.
- W98492166 workType "article" @default.