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- W98830747 abstract "Blood lipid values were determined in 48 normal, 56 subdiabetic and 6 overtly alloxan-diabetic rabbits before and after the initiation of experimental hypercholesterolaemia. Subdiabetes, induced by small doses of alloxan or by sequentially administered injections of cortisone and alloxan, is characterized by normoglyaemia changing to hyperglycaemia following repeated, normally nondiabetogenic small cortisone injections. Before cholesterol feeding, the subdiabetic rabbits attained considerably higher cholesterol, phospholipid, nonesterified fatty acid and total lipid levels than did the metabolically normal animals. The corresponding prefeeding levels of the alloxan-diabetic rabbits were also higher than normal, but their average cholesterol and phospholipid values remained lower than in the subdiabetic animals. During cholesterol feeding, the averages of all lipid fractions, especially in the subdiabetic and alloxan-diabetic animals, rose considerably for 8 weeks; thereafter, they tended to decline but continued to remain abnormally high, and only minor differences between the experimental groups persisted." @default.
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- W98830747 date "1971-06-01" @default.
- W98830747 modified "2023-09-26" @default.
- W98830747 title "Blood lipids in normal and subdiabetic rabbits before and after the induction of hypercholesterolaemia" @default.
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- W98830747 doi "https://doi.org/10.1007/bf01212552" @default.
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