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- W98890672 abstract "Profilin is one of the major components controlling actin polymerization. Here, profilin I was located in fibroblasts and HeLa cells by the use of two different sets of affinity-purified antibodies. Both antibody preparations labeled nuclei in a speckle-like pattern and displayed extensive colocalization with small nuclear ribonucleoprotein particle (snRNP)-core proteins and p80 coilin-containing Cajal bodies. Treatment with actinomycin D led to largely similar reorganizations of snRNPs and profilin, while profilin and Cajal bodies separated under these conditions. One of the profilin antibodies interfered with pre-mRNA splicing in vitro, further indicating a role for profilin during pre-mRNA processing." @default.
- W98890672 created "2016-06-24" @default.
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- W98890672 date "2003-05-01" @default.
- W98890672 modified "2023-09-24" @default.
- W98890672 title "Profilin I colocalizes with speckles and Cajal bodies:" @default.
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- W98890672 doi "https://doi.org/10.1016/s0014-4827(03)00102-2" @default.
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