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- W99004759 abstract "Publisher Summary This chapter focuses on foeto–maternal relationships. The spontaneous rosette-forming capacity of lymphocytes from pregnant donors is easily inhibited by ALS than the lymphocytes from nonpregnant donors or males. There is no variation in rosette inhibition test (RIT) relating to the menstrual cycle, contraceptive pills, or intercourse. An indirect RIT can be performed by preincubating nonpregnant donor lymphocytes with sera from pregnant donors. The indirect RIT has the advantage of quantitation, and this is expressed as a titre of study serum containing an early pregnancy factor required to alter RIT values. Direct and indirect RIT deviate from control values in patients who subsequently experience spontaneous abortion. The chapter discusses maternal serum factors, which inhibits in vitro responses of lymphocytes. Human placental conditioned medium stimulates hemopoietic colony formation by human marrow cells. Placental transferrin operates as a mechanism for iron transport across the placenta. In addition to possible iron transport and nonspecific resistance functions, coating of trophoblasts by maternal transferrin can serve a masking effect similar to that employed by some parasites, which coat themselves with host proteins to avoid immunosurveillance." @default.
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- W99004759 date "1977-01-01" @default.
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- W99004759 title "FOETO-MATERNAL RELATIONSHIPS" @default.
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