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- W99155583 abstract "An investigation was conducted on the separate and combined effects of lesions of the central nervous system and irradiation in tortoises. Eight tortoises were subjected to hemisection of the spinal cord at the level of the first cervical vertebra. This was followed by a marked reduction in the tone of the muscles of the hind limbs, particularly on the operated side, followed after 2 to 6 hours by some recovery of function, and subsequently by an increase in tone on the operated side. The skin sensitivity threshold of the hind limbs rose after operation, and there was a reduction in chronaxie followed by a rise, which returned to normal values after 8 to 10 days. A second group of 8 tortoises was subjected to hemisection followed immediately by x-irradiation in a dose of 5016 r. The tone of the muscles of the hind limbs was increased, but the tone of the muscles on the side of section fell after 4 to 5 days and the limb did not participate in locomotion. The skin sensitivity threshold on the operated side fell on the second day; this was followed by a rise which persisted for 10 to 12 days. On the unoperatedmore » side the threshold rose after section and remained at a high level. The chronaxia of the muscles of both hind limbs fell abruptly (from 1 to 0.2 v) and remained low until the death of the animal. In 8 other tortoises which were irradiated without previous spinal section there was no change in muscle tone in the hind limbs, but the skin sensitivity threshold rose markedly from 5 to 35 v and there was a fall in chronaxia. Similar experiments were carried out in white rats with lesions of the cerebellum, and it was found that the neurological disturbances were intensified by irradiation. (OTS)« less" @default.
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- W99155583 date "1960-01-01" @default.
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- W99155583 title "THE COURSE OF DAMAGE TO THE CENTRAL NERVOUS SYSTEM IN ANIMALS IRRADIATED WITH X-RAYS" @default.
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