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- W991835885 abstract "AbstractNegative emotions such as fear and acute stress elicit integrated enhancement of responses in the cardiovascular system, hypothalamo–pituitary–adrenocortical axis, and innate immunity. On the other hand, during experiences of positive emotions, secretion of central and peripheral dopamine and natural killer cell activity are enhanced without increased sympathetic activity. Such physiological responses accompanying emotions are not rigid and stereotyped but can be flexibly regulated by the brain on the basis of cognitive appraisal of the emotional situation. Using a combination of neuroimaging and physiological recording in humans, we have shown that a neural network that includes several portions of the prefrontal cortex and limbic regions plays a key role in the regulation of emotion. Furthermore, there are wide individual differences in the emotional reactivity in both negative and positive emotional domains. Genetic factors such as gene polymorphisms of the serotonin transporter gene and the opioid receptor gene can explain portions of the individual differences of emotional reactivity.KeywordsPositron Emission TomographyNatural Killer CellEmotion RegulationPositive EmotionNatural Killer Cell ActivityThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
- W991835885 created "2016-06-24" @default.
- W991835885 creator A5069219393 @default.
- W991835885 date "2011-01-01" @default.
- W991835885 modified "2023-09-24" @default.
- W991835885 title "Functional Association Between the Brain and Physiological Responses Accompanying Negative and Positive Emotions and Its Regulation by Genetic Factors" @default.
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- W991835885 doi "https://doi.org/10.1007/978-4-431-53892-9_18" @default.
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