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- W992013101 endingPage "345" @default.
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- W992013101 abstract "Both DNA and RNA nanostructures show exceptional programmability, modularity, and self-assembly ability. Using DNA or RNA molecules it is possible to assemble monodisperse particles that are homogeneous in size and shape and with identical positioning of surface modifications. For therapeutic applications such nanoparticles are of particular interest as they can be tailored to target cells and reduce unwanted side effects due to particle heterogeneity. Recently, DNA and RNA nanostructures have demonstrated this potential by delivery of drugs to specific cells in vitro and in vivo. This has launched an increasing interest to engineer-defined DNA and RNA vehicles for drug delivery. However, before this can be realized, key challenges must be overcome including structure integrity, efficient cell targeting, and drug release. The tunable nature of DNA and RNA assemblies allows for thorough investigations into various structural and functional features, which can address these challenges. To facilitate the synthesis process novel methods enable the construction of sophisticated structures and attachment of relevant functionalities. In this chapter we will discuss the state-of-the-art molecular designs and approaches to harness and use DNA and RNA nanostructures in drug delivery." @default.
- W992013101 created "2016-06-24" @default.
- W992013101 creator A5061426115 @default.
- W992013101 creator A5070935944 @default.
- W992013101 creator A5072940644 @default.
- W992013101 date "2014-01-01" @default.
- W992013101 modified "2023-09-27" @default.
- W992013101 title "Towards Defined DNA and RNA Delivery Vehicles Using Nucleic Acid Nanotechnology" @default.
- W992013101 cites W1514540900 @default.
- W992013101 cites W1585705786 @default.
- W992013101 cites W1847143559 @default.
- W992013101 cites W1966384509 @default.
- W992013101 cites W1966848207 @default.
- W992013101 cites W1968156574 @default.
- W992013101 cites W1971630118 @default.
- W992013101 cites W1975679096 @default.
- W992013101 cites W1976815031 @default.
- W992013101 cites W1977276757 @default.
- W992013101 cites W1977569147 @default.
- W992013101 cites W1977649256 @default.
- W992013101 cites W1981632082 @default.
- W992013101 cites W1988812533 @default.
- W992013101 cites W1991060977 @default.
- W992013101 cites W1992834282 @default.
- W992013101 cites W1994391392 @default.
- W992013101 cites W2000076998 @default.
- W992013101 cites W2006391873 @default.
- W992013101 cites W2008028087 @default.
- W992013101 cites W2008686601 @default.
- W992013101 cites W2009116600 @default.
- W992013101 cites W2011802753 @default.
- W992013101 cites W2013563809 @default.
- W992013101 cites W2014050554 @default.
- W992013101 cites W2014509855 @default.
- W992013101 cites W2015526636 @default.
- W992013101 cites W2017515700 @default.
- W992013101 cites W2018872681 @default.
- W992013101 cites W2020537808 @default.
- W992013101 cites W2021683440 @default.
- W992013101 cites W2023747155 @default.
- W992013101 cites W2024003310 @default.
- W992013101 cites W2024949907 @default.
- W992013101 cites W2030699288 @default.
- W992013101 cites W2032760352 @default.
- W992013101 cites W2032846952 @default.
- W992013101 cites W2033038899 @default.
- W992013101 cites W2033183276 @default.
- W992013101 cites W2035645019 @default.
- W992013101 cites W2036235120 @default.
- W992013101 cites W2038125628 @default.
- W992013101 cites W2038156304 @default.
- W992013101 cites W2040094175 @default.
- W992013101 cites W2040916104 @default.
- W992013101 cites W2043457044 @default.
- W992013101 cites W2044872860 @default.
- W992013101 cites W2057788156 @default.
- W992013101 cites W2058727626 @default.
- W992013101 cites W2067848116 @default.
- W992013101 cites W2068161092 @default.
- W992013101 cites W2069170784 @default.
- W992013101 cites W2069869069 @default.
- W992013101 cites W2071770240 @default.
- W992013101 cites W2072232974 @default.
- W992013101 cites W2072687635 @default.
- W992013101 cites W2072895616 @default.
- W992013101 cites W2074019806 @default.
- W992013101 cites W2076051065 @default.
- W992013101 cites W2077808289 @default.
- W992013101 cites W2077850544 @default.
- W992013101 cites W2078366331 @default.
- W992013101 cites W2079290717 @default.
- W992013101 cites W2082741569 @default.
- W992013101 cites W2084408879 @default.
- W992013101 cites W2085523918 @default.
- W992013101 cites W2089155556 @default.
- W992013101 cites W2091691458 @default.
- W992013101 cites W2094524922 @default.
- W992013101 cites W2095910786 @default.
- W992013101 cites W2099737063 @default.
- W992013101 cites W2103409481 @default.
- W992013101 cites W2104453796 @default.
- W992013101 cites W2105410188 @default.
- W992013101 cites W2105824455 @default.
- W992013101 cites W2111440720 @default.
- W992013101 cites W2112101570 @default.
- W992013101 cites W2112949283 @default.
- W992013101 cites W2117876468 @default.
- W992013101 cites W2119128096 @default.
- W992013101 cites W2121627241 @default.
- W992013101 cites W2125536449 @default.
- W992013101 cites W2126961173 @default.
- W992013101 cites W2128247929 @default.
- W992013101 cites W2129096474 @default.
- W992013101 cites W2133819505 @default.
- W992013101 cites W2136991395 @default.
- W992013101 cites W2140444174 @default.
- W992013101 cites W2141829963 @default.
- W992013101 cites W2145554986 @default.