Matches in SemOpenAlex for { <https://semopenalex.org/work/W99216986> ?p ?o ?g. }
- W99216986 abstract "To evaluate the levels of malondialdehyde (MDA) and total antioxidant capacity (TAC) in the blood and aqueous humor of glaucomatous and nonglaucomatous patients. To measure the adenosine triphosphate/adenosine diphosphate/adenosine monophosphate (ATP/ADP/AMP) concentration as a biomarker of the blood energy charge potential.We examined 40 consecutive patients with primary open-angle glaucoma scheduled for cataract surgery. Twenty-six age-matched subjects scheduled for cataract surgery were enrolled as a control group. Blood and aqueous humor samples were collected at the time of surgery. MDA concentrations and blood nucleotides were measured with high-performance liquid chromatography. The TAC of the samples was estimated with the oxygen-radical absorbance capacity method.Blood and aqueous humor MDA levels in glaucoma patients (respectively, 0.976±0.370 and 0.145±0.065 μmol/ml) were significantly increased (p<0.001 for both) over those of the control group (respectively, 0.454±0.395 and 0.060±0.039 μmol/ml). In contrast, the control group presented significantly higher TACs than did the glaucoma group in both the blood (control: 2.681±1.101 and glaucoma: 1.617±0.674 μmol Trolox Equi/g; p<0.001) and aqueous humor (control: 0.963±0.302 and glaucoma: 0.788±0.346 μmol Trolox Equi/g; p=0.039). The control group (0.869±0.037) exhibited statistically significant (p<0.001) higher values of blood adenosine triphosphate/adenosine diphosphate (ATP-ADP) levels than did the glaucoma group (0.791±0.037).Our data further support the hypothesis that oxidative stress and decreased antioxidant defenses are involved in glaucoma. High-performance liquid chromatography appears to be an effective and sensitive method to detect altered levels of oxidative stress markers in glaucoma patients." @default.
- W99216986 created "2016-06-24" @default.
- W99216986 creator A5006520350 @default.
- W99216986 creator A5007136526 @default.
- W99216986 creator A5007861700 @default.
- W99216986 creator A5026220949 @default.
- W99216986 creator A5056506879 @default.
- W99216986 creator A5056734505 @default.
- W99216986 creator A5060868918 @default.
- W99216986 creator A5069885135 @default.
- W99216986 creator A5070409102 @default.
- W99216986 creator A5071920540 @default.
- W99216986 date "2013-01-01" @default.
- W99216986 modified "2023-09-29" @default.
- W99216986 title "Increased malondialdehyde concentration and reduced total antioxidant capacity in aqueous humor and blood samples from patients with glaucoma." @default.
- W99216986 cites W1479732083 @default.
- W99216986 cites W1481168124 @default.
- W99216986 cites W1481720650 @default.
- W99216986 cites W1592657292 @default.
- W99216986 cites W1599257541 @default.
- W99216986 cites W1639442330 @default.
- W99216986 cites W1809573767 @default.
- W99216986 cites W1857619863 @default.
- W99216986 cites W195116966 @default.
- W99216986 cites W1975795035 @default.
- W99216986 cites W1979228140 @default.
- W99216986 cites W1985794479 @default.
- W99216986 cites W1986010820 @default.
- W99216986 cites W2016656152 @default.
- W99216986 cites W2028479043 @default.
- W99216986 cites W2040936867 @default.
- W99216986 cites W2049286672 @default.
- W99216986 cites W2054890136 @default.
- W99216986 cites W2057889917 @default.
- W99216986 cites W2061822628 @default.
- W99216986 cites W2068496420 @default.
- W99216986 cites W2072112660 @default.
- W99216986 cites W2074301486 @default.
- W99216986 cites W2078070842 @default.
- W99216986 cites W2082888717 @default.
- W99216986 cites W2095084064 @default.
- W99216986 cites W2105371260 @default.
- W99216986 cites W2111577111 @default.
- W99216986 cites W2125289626 @default.
- W99216986 cites W2153283566 @default.
- W99216986 cites W2161664666 @default.
- W99216986 cites W66851063 @default.
- W99216986 cites W97815548 @default.
- W99216986 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3742119" @default.
- W99216986 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23946639" @default.
- W99216986 hasPublicationYear "2013" @default.
- W99216986 type Work @default.
- W99216986 sameAs 99216986 @default.
- W99216986 citedByCount "41" @default.
- W99216986 countsByYear W992169862014 @default.
- W99216986 countsByYear W992169862015 @default.
- W99216986 countsByYear W992169862016 @default.
- W99216986 countsByYear W992169862017 @default.
- W99216986 countsByYear W992169862018 @default.
- W99216986 countsByYear W992169862019 @default.
- W99216986 countsByYear W992169862020 @default.
- W99216986 countsByYear W992169862021 @default.
- W99216986 countsByYear W992169862022 @default.
- W99216986 countsByYear W992169862023 @default.
- W99216986 crossrefType "journal-article" @default.
- W99216986 hasAuthorship W99216986A5006520350 @default.
- W99216986 hasAuthorship W99216986A5007136526 @default.
- W99216986 hasAuthorship W99216986A5007861700 @default.
- W99216986 hasAuthorship W99216986A5026220949 @default.
- W99216986 hasAuthorship W99216986A5056506879 @default.
- W99216986 hasAuthorship W99216986A5056734505 @default.
- W99216986 hasAuthorship W99216986A5060868918 @default.
- W99216986 hasAuthorship W99216986A5069885135 @default.
- W99216986 hasAuthorship W99216986A5070409102 @default.
- W99216986 hasAuthorship W99216986A5071920540 @default.
- W99216986 hasConcept C118487528 @default.
- W99216986 hasConcept C126322002 @default.
- W99216986 hasConcept C185592680 @default.
- W99216986 hasConcept C2775888743 @default.
- W99216986 hasConcept C2776231299 @default.
- W99216986 hasConcept C2776991684 @default.
- W99216986 hasConcept C2778004101 @default.
- W99216986 hasConcept C2778401633 @default.
- W99216986 hasConcept C2778527774 @default.
- W99216986 hasConcept C2779876172 @default.
- W99216986 hasConcept C2781150145 @default.
- W99216986 hasConcept C2993539680 @default.
- W99216986 hasConcept C55493867 @default.
- W99216986 hasConcept C71924100 @default.
- W99216986 hasConceptScore W99216986C118487528 @default.
- W99216986 hasConceptScore W99216986C126322002 @default.
- W99216986 hasConceptScore W99216986C185592680 @default.
- W99216986 hasConceptScore W99216986C2775888743 @default.
- W99216986 hasConceptScore W99216986C2776231299 @default.
- W99216986 hasConceptScore W99216986C2776991684 @default.
- W99216986 hasConceptScore W99216986C2778004101 @default.
- W99216986 hasConceptScore W99216986C2778401633 @default.
- W99216986 hasConceptScore W99216986C2778527774 @default.
- W99216986 hasConceptScore W99216986C2779876172 @default.
- W99216986 hasConceptScore W99216986C2781150145 @default.