Matches in SemOpenAlex for { <https://semopenalex.org/work/W993037274> ?p ?o ?g. }
Showing items 1 to 54 of
54
with 100 items per page.
- W993037274 endingPage "6586" @default.
- W993037274 startingPage "6580" @default.
- W993037274 abstract "背景：超声治疗能够缓解疼痛，改善膝骨关节炎患者的运动功能，但目前关于超声治疗的文献缺乏一致性。目的：进一步验证超声治疗的膝骨关节炎有效性。方法：24只兔子随机分为3组，正常组不干预；模型组兔行前交叉韧带离断诱导膝骨关节炎，不接受任何治疗；超声组兔建模后接受超声波治疗10min／次，1次／d，0．3W／cm2，1MHz，共治疗10次。采用苏木精一伊红染色进行兔关节软骨组织学观察，运用免疫印迹和RT-PCR技术检测兔软骨中的caspases3和caspases8的表达，TUNEL技术检测兔膝骨关节软骨细胞凋亡率。结果与结论：正常兔软骨组织软骨细胞呈柱状整齐的排列，模型中软骨层变薄，软骨细胞排列无序而少。超声治疗后软骨细胞重新排列，趋于整齐，细胞数增加。模型组为膝骨关节炎模型；与正常组比较，模型组和超声组改良Mankin评分较高，模型组和超声组软骨细胞凋亡指数更高，模型组高于超声组。与正常组比较，模型组和超声组caspase．3和caspase．8表达较高，超声治疗后两项指标表达下降。结果表明，超声可以改善软骨组织结构、降低caspase．3、caspase．8的表达，降低软骨细胞凋亡。提示超声治疗膝骨关节炎是有效的。" @default.
- W993037274 created "2016-06-24" @default.
- W993037274 creator A5038375764 @default.
- W993037274 creator A5042395967 @default.
- W993037274 creator A5045950237 @default.
- W993037274 creator A5047962643 @default.
- W993037274 creator A5080055027 @default.
- W993037274 date "2013-09-10" @default.
- W993037274 modified "2023-09-23" @default.
- W993037274 title "超声对软骨细胞凋亡、caspase-8和caspase-3表达的影响" @default.
- W993037274 doi "https://doi.org/10.3969/j.issn.2095-4344.2013.37.007" @default.
- W993037274 hasPublicationYear "2013" @default.
- W993037274 type Work @default.
- W993037274 sameAs 993037274 @default.
- W993037274 citedByCount "0" @default.
- W993037274 crossrefType "journal-article" @default.
- W993037274 hasAuthorship W993037274A5038375764 @default.
- W993037274 hasAuthorship W993037274A5042395967 @default.
- W993037274 hasAuthorship W993037274A5045950237 @default.
- W993037274 hasAuthorship W993037274A5047962643 @default.
- W993037274 hasAuthorship W993037274A5080055027 @default.
- W993037274 hasConcept C1186008 @default.
- W993037274 hasConcept C12519072 @default.
- W993037274 hasConcept C190283241 @default.
- W993037274 hasConcept C31573885 @default.
- W993037274 hasConcept C41008148 @default.
- W993037274 hasConcept C48297814 @default.
- W993037274 hasConcept C55493867 @default.
- W993037274 hasConcept C86803240 @default.
- W993037274 hasConcept C91096171 @default.
- W993037274 hasConcept C95444343 @default.
- W993037274 hasConcept C98424977 @default.
- W993037274 hasConceptScore W993037274C1186008 @default.
- W993037274 hasConceptScore W993037274C12519072 @default.
- W993037274 hasConceptScore W993037274C190283241 @default.
- W993037274 hasConceptScore W993037274C31573885 @default.
- W993037274 hasConceptScore W993037274C41008148 @default.
- W993037274 hasConceptScore W993037274C48297814 @default.
- W993037274 hasConceptScore W993037274C55493867 @default.
- W993037274 hasConceptScore W993037274C86803240 @default.
- W993037274 hasConceptScore W993037274C91096171 @default.
- W993037274 hasConceptScore W993037274C95444343 @default.
- W993037274 hasConceptScore W993037274C98424977 @default.
- W993037274 hasIssue "37" @default.
- W993037274 hasLocation W9930372741 @default.
- W993037274 hasOpenAccess W993037274 @default.
- W993037274 hasPrimaryLocation W9930372741 @default.
- W993037274 hasVolume "17" @default.
- W993037274 isParatext "false" @default.
- W993037274 isRetracted "false" @default.
- W993037274 magId "993037274" @default.
- W993037274 workType "article" @default.