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- W993469717 abstract "目的探讨检测TGF-β1、Smad4、VEGF的表达与大肠癌转移、复发的关系，分析其在大肠癌预后的意义。方法将病理确诊的大肠癌60例患者，按术后2～5年内有无临床复发、转移分为复发转移组30例和无瘤生存组30例，并进行TGF-β1、Smad4、VEGF免疫组化染色。结果TGF-β1及VEGF在复发转移组大肠癌组织中的表达水平明显高于无瘤生存组大肠癌组织，差异有显著性（P均〈0．05）。Smad4在复发转移组大肠癌组织中的表达水平明显低于无瘤生存组（P〈0．05）。结论TGF-β1在复发大肠癌组织中的表达上调，但其表达受Smad4的调控，而导致VEGF的表达上调可能参与大肠肿瘤复发与转移。" @default.
- W993469717 created "2016-06-24" @default.
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- W993469717 date "2007-01-01" @default.
- W993469717 modified "2023-09-24" @default.
- W993469717 title "TGF-β1及Smad4、VEGF与大肠癌术后近期复发的关系" @default.
- W993469717 hasPublicationYear "2007" @default.
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