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• W99359245 endingPage "119" @default.
• W99359245 startingPage "95" @default.
• W99359245 abstract "The skeletal muscle cell system provides a powerful model for exploring the mechanistic basis for the antagonism between cell growth and differentiation. The recent identification of the MyoD family of muscle-specific transcription factors now offers opportunities to dissect at the molecular level of the mechanisms through which defined cell type-specific transcription factors can activate an entire differentiation program as well as to unravel the mechanisms through which growth factor and oncogenic signals can disrupt cellular differentiation. Because the mechanisms for growth factor signaling and induction of cell proliferation are conserved in diverse cell types, it is tempting to speculate that the molecular mechanisms responsible for the antagonism between cell proliferation and differentiation in muscle cells are also operative in other cell types. Resolution of this question, however, must await identification of the regulatory factors that specify cell fate in other lineages." @default.
• W99359245 created "2016-06-24" @default.
• W99359245 creator A5027475930 @default.
• W99359245 creator A5084182062 @default.
• W99359245 date "1992-01-01" @default.
• W99359245 modified "2023-10-15" @default.
• W99359245 title "Regulation of Muscle Cell Growth and Differentiation by the Myod Family of Helix-Loop-Helix Proteins" @default.
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