Matches in SemOpenAlex for { <https://semopenalex.org/work/W99690375> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W99690375 endingPage "82" @default.
- W99690375 startingPage "166" @default.
- W99690375 abstract "Exposure to a sublethal concentration of methyl parathion (MEP) reduced the activity of cytoplasmic malate dehydrogenase, mitochondrial malate dehydrogenase, and lactate dehydrogenase by 30 to 49% in the liver and the skeletal muscle of the freshwater catfish. Clarias batrachus, after 7 days. The activities then began to recover and reached the control levels on the 28th day of MEP exposure. A complete recovery occurred on the 7th day when MEP was withdrawn from the medium after an exposure for 1 week. The withdrawal-dependent recovery in the activities was inhibited partially or completely by actinomycin D and cycloheximide, suggesting de novo synthesis of the enzymes during the recovery period. A conjoint treatment of MEP and triiodothyronine (T3) restored the activities to control levels, indicating T3 protection against the pesticide toxicity. SDS-PAGE of the cytoplasmic fraction of the liver showed some noticeable changes in the protein pattern after an exposure to MEP. Ultrastructural studies on MEP-treated liver cells showed disappearance of the glycogen granules and appearance of numerous smooth endoplasmic reticulum, lysosomal dense bodies, and swollen mitochondria. These changes in the liver are an indication of hepatic toxicity leading toward necrosis." @default.
- W99690375 created "2016-06-24" @default.
- W99690375 creator A5054792901 @default.
- W99690375 creator A5069945617 @default.
- W99690375 date "1990-06-01" @default.
- W99690375 modified "2023-09-23" @default.
- W99690375 title "Enzymatic and ultrastructural studies in a freshwater catfish: impact of methyl parathion." @default.
- W99690375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2099789" @default.
- W99690375 hasPublicationYear "1990" @default.
- W99690375 type Work @default.
- W99690375 sameAs 99690375 @default.
- W99690375 citedByCount "3" @default.
- W99690375 countsByYear W996903752016 @default.
- W99690375 countsByYear W996903752018 @default.
- W99690375 crossrefType "journal-article" @default.
- W99690375 hasAuthorship W99690375A5054792901 @default.
- W99690375 hasAuthorship W99690375A5069945617 @default.
- W99690375 hasConcept C126322002 @default.
- W99690375 hasConcept C132901563 @default.
- W99690375 hasConcept C134018914 @default.
- W99690375 hasConcept C161176658 @default.
- W99690375 hasConcept C16685009 @default.
- W99690375 hasConcept C181199279 @default.
- W99690375 hasConcept C185592680 @default.
- W99690375 hasConcept C2776317432 @default.
- W99690375 hasConcept C2776823892 @default.
- W99690375 hasConcept C2777318727 @default.
- W99690375 hasConcept C2777499176 @default.
- W99690375 hasConcept C2778128677 @default.
- W99690375 hasConcept C28859421 @default.
- W99690375 hasConcept C29730261 @default.
- W99690375 hasConcept C3675279 @default.
- W99690375 hasConcept C55493867 @default.
- W99690375 hasConcept C6557445 @default.
- W99690375 hasConcept C71924100 @default.
- W99690375 hasConcept C86803240 @default.
- W99690375 hasConceptScore W99690375C126322002 @default.
- W99690375 hasConceptScore W99690375C132901563 @default.
- W99690375 hasConceptScore W99690375C134018914 @default.
- W99690375 hasConceptScore W99690375C161176658 @default.
- W99690375 hasConceptScore W99690375C16685009 @default.
- W99690375 hasConceptScore W99690375C181199279 @default.
- W99690375 hasConceptScore W99690375C185592680 @default.
- W99690375 hasConceptScore W99690375C2776317432 @default.
- W99690375 hasConceptScore W99690375C2776823892 @default.
- W99690375 hasConceptScore W99690375C2777318727 @default.
- W99690375 hasConceptScore W99690375C2777499176 @default.
- W99690375 hasConceptScore W99690375C2778128677 @default.
- W99690375 hasConceptScore W99690375C28859421 @default.
- W99690375 hasConceptScore W99690375C29730261 @default.
- W99690375 hasConceptScore W99690375C3675279 @default.
- W99690375 hasConceptScore W99690375C55493867 @default.
- W99690375 hasConceptScore W99690375C6557445 @default.
- W99690375 hasConceptScore W99690375C71924100 @default.
- W99690375 hasConceptScore W99690375C86803240 @default.
- W99690375 hasIssue "2" @default.
- W99690375 hasLocation W996903751 @default.
- W99690375 hasOpenAccess W99690375 @default.
- W99690375 hasPrimaryLocation W996903751 @default.
- W99690375 hasRelatedWork W1979831618 @default.
- W99690375 hasRelatedWork W1983281557 @default.
- W99690375 hasRelatedWork W2019304997 @default.
- W99690375 hasRelatedWork W2059973977 @default.
- W99690375 hasRelatedWork W2061338339 @default.
- W99690375 hasRelatedWork W2067057332 @default.
- W99690375 hasRelatedWork W2067420064 @default.
- W99690375 hasRelatedWork W2148328115 @default.
- W99690375 hasRelatedWork W2343491079 @default.
- W99690375 hasRelatedWork W2496986534 @default.
- W99690375 hasVolume "3" @default.
- W99690375 isParatext "false" @default.
- W99690375 isRetracted "false" @default.
- W99690375 magId "99690375" @default.
- W99690375 workType "article" @default.