Matches in SemOpenAlex for { <https://semopenalex.org/work/W996913470> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W996913470 endingPage "308" @default.
- W996913470 startingPage "299" @default.
- W996913470 abstract "The effects of cisplatin, sodium selenite and a conjugate of these compounds [(NH3)2Pt(SeO3)] on the generation of free radicals in blood platelets measured by chemiluminescence method were investigated in vitro. In platelets incubated with cisplatin (20 microM, 5 min) a dose-dependent increase of chemiluminescence was observed (p < 0.05). Contrary to the stimulatory action of cisplatin (20 microM) on the production of free radicals, selenite (1 microM) and its conjugate with cisplatin (20 microM) had only slight effects on the oxidative stress in platelets (p < 0.05). The observed increase of chemiluminescence after cisplatin action correlated with a decrease of platelet free thiols present in reduced glutathione. Pre-treatment of blood platelets with buthionine sulfoximine (50 microM, 1 h, 37 degrees C) leading to a decrease of glutathione reduced the cisplatin-induced generation of free radicals in these cells (p < 0.05)." @default.
- W996913470 created "2016-06-24" @default.
- W996913470 creator A5018890878 @default.
- W996913470 creator A5068540539 @default.
- W996913470 creator A5069339462 @default.
- W996913470 creator A5075386451 @default.
- W996913470 creator A5076958160 @default.
- W996913470 date "1999-06-01" @default.
- W996913470 modified "2023-10-18" @default.
- W996913470 title "The effect of cis-diamminedichloroplatinum, selenite and a conjugate of cisplatin with selenite [(NH3)2Pt(SeO3)] on oxidative stress in blood platelets measured by chemiluminescence method." @default.
- W996913470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10424724" @default.
- W996913470 hasPublicationYear "1999" @default.
- W996913470 type Work @default.
- W996913470 sameAs 996913470 @default.
- W996913470 citedByCount "1" @default.
- W996913470 crossrefType "journal-article" @default.
- W996913470 hasAuthorship W996913470A5018890878 @default.
- W996913470 hasAuthorship W996913470A5068540539 @default.
- W996913470 hasAuthorship W996913470A5069339462 @default.
- W996913470 hasAuthorship W996913470A5075386451 @default.
- W996913470 hasAuthorship W996913470A5076958160 @default.
- W996913470 hasConcept C126322002 @default.
- W996913470 hasConcept C134306372 @default.
- W996913470 hasConcept C139066938 @default.
- W996913470 hasConcept C145802702 @default.
- W996913470 hasConcept C178790620 @default.
- W996913470 hasConcept C181199279 @default.
- W996913470 hasConcept C185592680 @default.
- W996913470 hasConcept C197336794 @default.
- W996913470 hasConcept C2776151105 @default.
- W996913470 hasConcept C2776694085 @default.
- W996913470 hasConcept C2777476445 @default.
- W996913470 hasConcept C2778239845 @default.
- W996913470 hasConcept C33923547 @default.
- W996913470 hasConcept C43617362 @default.
- W996913470 hasConcept C48349386 @default.
- W996913470 hasConcept C538909803 @default.
- W996913470 hasConcept C553756173 @default.
- W996913470 hasConcept C55493867 @default.
- W996913470 hasConcept C71924100 @default.
- W996913470 hasConcept C89560881 @default.
- W996913470 hasConceptScore W996913470C126322002 @default.
- W996913470 hasConceptScore W996913470C134306372 @default.
- W996913470 hasConceptScore W996913470C139066938 @default.
- W996913470 hasConceptScore W996913470C145802702 @default.
- W996913470 hasConceptScore W996913470C178790620 @default.
- W996913470 hasConceptScore W996913470C181199279 @default.
- W996913470 hasConceptScore W996913470C185592680 @default.
- W996913470 hasConceptScore W996913470C197336794 @default.
- W996913470 hasConceptScore W996913470C2776151105 @default.
- W996913470 hasConceptScore W996913470C2776694085 @default.
- W996913470 hasConceptScore W996913470C2777476445 @default.
- W996913470 hasConceptScore W996913470C2778239845 @default.
- W996913470 hasConceptScore W996913470C33923547 @default.
- W996913470 hasConceptScore W996913470C43617362 @default.
- W996913470 hasConceptScore W996913470C48349386 @default.
- W996913470 hasConceptScore W996913470C538909803 @default.
- W996913470 hasConceptScore W996913470C553756173 @default.
- W996913470 hasConceptScore W996913470C55493867 @default.
- W996913470 hasConceptScore W996913470C71924100 @default.
- W996913470 hasConceptScore W996913470C89560881 @default.
- W996913470 hasIssue "2" @default.
- W996913470 hasLocation W9969134701 @default.
- W996913470 hasOpenAccess W996913470 @default.
- W996913470 hasPrimaryLocation W9969134701 @default.
- W996913470 hasRelatedWork W151843294 @default.
- W996913470 hasRelatedWork W2035796149 @default.
- W996913470 hasRelatedWork W2046560085 @default.
- W996913470 hasRelatedWork W2059094815 @default.
- W996913470 hasRelatedWork W2083356413 @default.
- W996913470 hasRelatedWork W2106465332 @default.
- W996913470 hasRelatedWork W2188573252 @default.
- W996913470 hasRelatedWork W2416932467 @default.
- W996913470 hasRelatedWork W2560226641 @default.
- W996913470 hasRelatedWork W996913470 @default.
- W996913470 hasVolume "50" @default.
- W996913470 isParatext "false" @default.
- W996913470 isRetracted "false" @default.
- W996913470 magId "996913470" @default.
- W996913470 workType "article" @default.