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• W99741135 abstract "Clinical data show that a 1% increase in serum concentrations of high-density lipoprotein cholesterol (HDL-C) can decrease cardiovascular risk by 2% to 3%. Therefore, mechanisms affecting the level and functionality of high-density lipoprotein (HDL) and its constituents are being investigated as targets for the rational development of drugs to prevent or treat cardiovascular disease. High-density lipoprotein-related research may also increase our understanding of the link between atherosclerosis and metabolic disorders. This report and update of the HDL Working Group discusses HDL metabolism and reverse cholesterol transport, impaired HDL as a marker and a cause of proatherogenic states, and experimental and current approaches to HDL-related therapy." @default.
• W99741135 created "2016-06-24" @default.
• W99741135 creator A5020230532 @default.
• W99741135 creator A5068202304 @default.
• W99741135 date "2004-03-01" @default.
• W99741135 modified "2023-10-17" @default.
• W99741135 title "Assessing low levels of high-density lipoprotein cholesterol as a risk factor in coronary heart disease" @default.
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• W99741135 doi "https://doi.org/10.1016/j.jacc.2003.08.061" @default.
• W99741135 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14998606" @default.
• W99741135 hasPublicationYear "2004" @default.
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