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- W997804961 abstract "Epidural or spinal haematoma caused by the association of antithrombotic drugs and central neural block is a rare but devastating complication. The severity of the neurological consequences has to be carefully considered and case reports are still published. Furthermore, there are undoubtedly unreported cases. Very few accidents have been reported with antiplatelet agents, when no additional anticoagulant therapy is added pre or post-operatively. Spinal blockade could probably be performed safely, providing that no other hemorrhagic risk factor is recorded. Conversely, recent reports of the Food and Drug Administration have reminded us the potential danger of the association of LMWH with loco-regional anaesthesia. Forty-three accidents with epidural or spinal haematomas have been reported in the USA since 1993. This report emphasized the suspected predisposing factors for haematoma, including excessive dosage of LMWH administration of LMWH before the establishment of haemostasis, use of epidural catheters, administration of concomitant medications known to increase bleeding, presence of vertebral-column abnormalities, older age, female sex. Obviously, the association of heparin and antiplatelet agents is critical." @default.
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- W997804961 modified "2023-09-23" @default.
- W997804961 title "Is loco-regional spinal anaesthesia possible in patients treated with one or more antithrombotic drugs?" @default.
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