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- W997861837 abstract "Glutamate is a principal neurotransmitter in lower vertebrate retina, which is employed by photoreceptors and bipolar cells[1]. Photoreceptors encode a light signal as a concentration change of glutamate. In the dark, glutamate is tonically released from the photoreceptor terminal into the synaptic cleft, where it acts on channels in postsynaptic horizontal cells. Light-induced hyperpolarization of photoreceptor causes a decrease of glutamate release, and as a result, membrane potential change is generated in the horizontal cells. Since there are no extracellular enzymes to inactivate the glutamate action in the synaptic cleft, glutamate is thought to be removed from the cleft by an uptake mechanism in photoreceptor, or by diffusion away which is uptaken by glial cells. However, the real-time process of the glutamate release has not been measured[2] because of a lack of experimental techniques for an intact retina." @default.
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- W997861837 date "1993-01-01" @default.
- W997861837 modified "2023-09-23" @default.
- W997861837 title "Effects of Glutamate Uptake on the Response Dynamics of the Retinal Horizontal Cell" @default.
- W997861837 cites W1993019181 @default.
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- W997861837 doi "https://doi.org/10.1007/978-1-4471-2063-6_49" @default.
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