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- W99793243 abstract "The aim of this chapter is to review some of the recent work on tumor immunity. A certain degree of overlap is inevitable in order to assess the value of the most recent advances. Geneticists, those engaged in the study of chemotherapy and others interested in “tumor immunity,” have had no training in immunology. The sequence of events that results in the rejection of an incompatible graft of either normal or malignant tissue is known as the homograft reaction. The chapter explores that in actively immunized animals the graft is not vascularized, but is rapidly surrounded by the host's leucocytes. Ascites tumors proliferate as free cells in the peritoneal cavity without any vasculature. These cells advance in a syncytial mass and encircle individual malignant cells. As a rule, the malignant cells are killed, the encircling histiocytes become engorged with phagocytosed material. and may disintegrate. However, occasionally the histiocytes may die and be phagocytosed by the malignant cells. The chapter also discusses the concept of adoptive immunity. It is now well established that cells derived from spleen and lymph nodes may be transferred to other individuals and render them susceptible to various types of allergy and produce circulating antibodies." @default.
- W99793243 created "2016-06-24" @default.
- W99793243 creator A5013039279 @default.
- W99793243 date "1956-01-01" @default.
- W99793243 modified "2023-10-15" @default.
- W99793243 title "Some Recent Work on Tumor Immunity" @default.
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- W99793243 doi "https://doi.org/10.1016/s0065-230x(08)60724-1" @default.
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