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- W998567227 abstract "以中国荷斯坦奶牛（Chinese Holstein dairy cattle）为对象,以α1-抗胰蛋白酶基因（α1-AT）为候选基因,扩增5′侧翼区668 bp和999 bp的片段并进行测序.首次发现,在＋3 142 bp处P1和＋4 408 bp处P2分别发生C-T、T-C突变.随后采用PCR-RFLP方法对随机采自6个牛场,共计294头牛进行了检测,遗传变异和产奶性状分析结果显示：2个位点的等位基因在群体中都有分布,且处于中度多态.P1位点A和B等位基因的频率分别为50.34%和49.66%;AA、AB和BB基因型频率分别为23.81%、53.06%和23.13%;P2位点E和F等位基因的频率分别为30.61%和69.39%,EE、EF和FF基因型频率分别为11.90%、37.41%和50.68%.χ2适合性检验表明,该群体在P1位点的突变达到Hardy-Weinberg平衡状态（P〉0.05）,在P2位点未达到平衡.基因与产奶性状关联分析表明,AB基因型个体产奶量与脂蛋比显著高于AA基因型个体（P〈0.05）;FF基因型个体乳蛋白率显著高于EF基因型个体（P〈0.05）;9种单倍型组合与乳脂率、乳蛋白率、体细胞数、产奶量及脂蛋比均存在不同程度相关性." @default.
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- W998567227 date "2009-01-01" @default.
- W998567227 modified "2023-09-23" @default.
- W998567227 title "牛α1-抗胰蛋白酶基因5′侧翼区新SNP的鉴定及其与中国荷斯坦奶牛产奶性状的相关性" @default.
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