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- W99920373 abstract "Acute nontraumatic lower limb ischemia is associated with very high mortality rates, often exceeding 25%[1–3]. Systemic atherosclerotic cardiovascular disease is present in most of these patients and the clinical risk index is therefore usually high due to old age, congestive heart failure, prior myocardial infarction, prior stroke, arrhythmia and abnormal electrocardiogram [4–6]. Acute arterial ischemia results in a high degree of energy metabolic impairment in the muscle [7] and the ischemic leg constitutes a source of complement activation increasing plasma anaphylatoxin concentrations [8], which in turn may further impair cardiac function [9]. Mortality in connection with acute limb ischemia seems related to the severity of the metabolic consequences of the ischemia, i.e. to the amount of tissue involved and the severity and duration of the circulatory disturbance.KeywordsArterial EmbolismLimb IschemiaHeparin InfusionLower Limb IschemiaAcute Limb IschemiaThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W99920373 date "1990-01-01" @default.
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- W99920373 title "Emergency Management of Acute Lower Limb Ischemia" @default.
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