Matches in Ubergraph for { <http://purl.obolibrary.org/obo/FBcv_0007044> ?p ?o ?g. }
Showing items 1 to 18 of
18
with 100 items per page.
- FBcv_0007044 IAO_0000115 "A docking element is an element that has been introduced into a site in the genome to allow integration of DNA at a defined location; this neutralizes the problem of position effects that are seen with non-specific insertion techniques such as transposable-element-mediated transgenesis. A docking element contains a single target site for an integrase, allowing subsequent integration of DNA into this site from a donor element via integrase mediated recombination. The docking element in the genome typically contains the 'attB' site and the donor plasmid contains the 'attP' site, since this directionality gives higher integration rates compared to the alternative combination where the 'attB' site is integrated into the genome. A docking element insertion is typically selected to be 'benign' (that is it does not result in disruption of an endogenous locus) and to show a high rate of integration in the presence of integrase." @default.
- FBcv_0007044 contributor 0000-0002-1373-1705 @default.
- FBcv_0007044 date "2020-02-03T15:54:09.000Z" @default.
- FBcv_0007044 normalizedInformationContent "100" @default.
- FBcv_0007044 referenceCount "1" @default.
- FBcv_0007044 hasExactSynonym "docking site element" @default.
- FBcv_0007044 hasExactSynonym "landing site element" @default.
- FBcv_0007044 hasOBONamespace "experimental_tool_descriptor" @default.
- FBcv_0007044 id "FBcv:0007044" @default.
- FBcv_0007044 type Class @default.
- FBcv_0007044 comment "This includes any element containing a single site for integrase-mediated integration, as in FBrf0231034 Fig 10a, but not elements with multiple integrase sites, as in FBrf0231034 Fig 10b (see FBcv:0007042 - RMCE target element). Elements with sites for recombinase-mediated exchange (as in FBrf0231034 Fig 10c) are only included if they additionally carry exactly one integrase site for integrase-mediated integration." @default.
- FBcv_0007044 isDefinedBy fbcv.owl @default.
- FBcv_0007044 label "docking element" @default.
- FBcv_0007044 subClassOf FBcv_0000000 @default.
- FBcv_0007044 subClassOf FBcv_0000013 @default.
- FBcv_0007044 subClassOf FBcv_0005001 @default.
- FBcv_0007044 subClassOf FBcv_0005075 @default.
- FBcv_0007044 subClassOf FBcv_0007044 @default.