Matches in Ubergraph for { <http://purl.obolibrary.org/obo/HP_0008151> ?p ?o ?g. }
- HP_0008151 BFO_0000051 BFO_0000001 @default.
- HP_0008151 BFO_0000051 BFO_0000002 @default.
- HP_0008151 BFO_0000051 BFO_0000020 @default.
- HP_0008151 BFO_0000051 COB_0000502 @default.
- HP_0008151 BFO_0000051 FYPO_0000001 @default.
- HP_0008151 BFO_0000051 OBA_0000001 @default.
- HP_0008151 BFO_0000051 OBA_0100002 @default.
- HP_0008151 BFO_0000051 OBA_0100003 @default.
- HP_0008151 BFO_0000051 OBA_1000617 @default.
- HP_0008151 BFO_0000051 PATO_0000001 @default.
- HP_0008151 COB_0000047 BFO_0000001 @default.
- HP_0008151 COB_0000047 BFO_0000002 @default.
- HP_0008151 COB_0000047 BFO_0000020 @default.
- HP_0008151 COB_0000047 COB_0000502 @default.
- HP_0008151 COB_0000047 FYPO_0000001 @default.
- HP_0008151 COB_0000047 OBA_0000001 @default.
- HP_0008151 COB_0000047 OBA_0100002 @default.
- HP_0008151 COB_0000047 OBA_0100003 @default.
- HP_0008151 COB_0000047 OBA_1000617 @default.
- HP_0008151 COB_0000047 PATO_0000001 @default.
- HP_0008151 IAO_0000115 "Increased time to coagulation in the prothrombin time test, which is a measure of the extrinsic pathway of coagulation. The results of the prothrombin time test are often expressed in terms of the International normalized ratio (INR), which is calculated as a ratio of the patient's prothrombin time (PT) to a control PT standardized for the potency of the thromboplastin reagent developed by the World Health Organization (WHO) using the formula: INR is equal to Patient PT divided by Control PT." @default.
- HP_0008151 RO_0002131 BFO_0000001 @default.
- HP_0008151 RO_0002131 BFO_0000002 @default.
- HP_0008151 RO_0002131 BFO_0000020 @default.
- HP_0008151 RO_0002131 COB_0000502 @default.
- HP_0008151 RO_0002131 FYPO_0000001 @default.
- HP_0008151 RO_0002131 OBA_0000001 @default.
- HP_0008151 RO_0002131 OBA_0100002 @default.
- HP_0008151 RO_0002131 OBA_0100003 @default.
- HP_0008151 RO_0002131 OBA_1000617 @default.
- HP_0008151 RO_0002131 PATO_0000001 @default.
- HP_0008151 RO_0002323 BFO_0000001 @default.
- HP_0008151 RO_0002323 BFO_0000002 @default.
- HP_0008151 RO_0002323 BFO_0000020 @default.
- HP_0008151 RO_0002323 COB_0000502 @default.
- HP_0008151 RO_0002323 FYPO_0000001 @default.
- HP_0008151 RO_0002323 OBA_0000001 @default.
- HP_0008151 RO_0002323 OBA_0100002 @default.
- HP_0008151 RO_0002323 OBA_0100003 @default.
- HP_0008151 RO_0002323 OBA_1000617 @default.
- HP_0008151 RO_0002323 PATO_0000001 @default.
- HP_0008151 UPHENO_0000001 BFO_0000001 @default.
- HP_0008151 UPHENO_0000001 BFO_0000002 @default.
- HP_0008151 UPHENO_0000001 BFO_0000003 @default.
- HP_0008151 UPHENO_0000001 BFO_0000004 @default.
- HP_0008151 UPHENO_0000001 BFO_0000015 @default.
- HP_0008151 UPHENO_0000001 BFO_0000040 @default.
- HP_0008151 UPHENO_0000001 CARO_0000000 @default.
- HP_0008151 UPHENO_0000001 CARO_0000006 @default.
- HP_0008151 UPHENO_0000001 CARO_0001008 @default.
- HP_0008151 UPHENO_0000001 CARO_0001010 @default.
- HP_0008151 UPHENO_0000001 CARO_0010000 @default.
- HP_0008151 UPHENO_0000001 CARO_0010004 @default.
- HP_0008151 UPHENO_0000001 COB_0000006 @default.
- HP_0008151 UPHENO_0000001 COB_0000021 @default.
- HP_0008151 UPHENO_0000001 COB_0000022 @default.
- HP_0008151 UPHENO_0000001 COB_0000034 @default.
- HP_0008151 UPHENO_0000001 COB_0000037 @default.
- HP_0008151 UPHENO_0000001 COB_0000118 @default.
- HP_0008151 UPHENO_0000001 FYPO_0000001 @default.
- HP_0008151 UPHENO_0000001 GO_0008150 @default.
- HP_0008151 UPHENO_0000001 GO_0032501 @default.
- HP_0008151 UPHENO_0000001 GO_0050817 @default.
- HP_0008151 UPHENO_0000001 NCBITaxon_1 @default.
- HP_0008151 UPHENO_0000001 NCBITaxon_131567 @default.
- HP_0008151 UPHENO_0000001 OBI_0100026 @default.
- HP_0008151 UPHENO_0000001 PCO_0000031 @default.
- HP_0008151 UPHENO_0000001 UBERON_0000061 @default.
- HP_0008151 UPHENO_0000001 UBERON_0000465 @default.
- HP_0008151 UPHENO_0000001 UBERON_0000467 @default.
- HP_0008151 UPHENO_0000001 UBERON_0000468 @default.
- HP_0008151 UPHENO_0000001 UBERON_0001062 @default.
- HP_0008151 UPHENO_0000001 UBERON_0002193 @default.
- HP_0008151 UPHENO_0000001 UBERON_0002390 @default.
- HP_0008151 UPHENO_0000001 UBERON_0004120 @default.
- HP_0008151 UPHENO_0000001 UBERON_0010000 @default.
- HP_0008151 normalizedInformationContent "100" @default.
- HP_0008151 referenceCount "1" @default.
- HP_0008151 hasAlternativeId "HP:0012201" @default.
- HP_0008151 hasDbXref "SNOMEDCT_US:409674002" @default.
- HP_0008151 hasDbXref "UMLS:C0151872" @default.
- HP_0008151 hasExactSynonym "Increased INR" @default.
- HP_0008151 hasExactSynonym "Increased international normalised ratio" @default.
- HP_0008151 hasExactSynonym "Increased international normalized ratio" @default.
- HP_0008151 hasExactSynonym "Low factor II activity" @default.
- HP_0008151 hasExactSynonym "Prolonged PT" @default.
- HP_0008151 hasExactSynonym "Reduced factor II activity" @default.
- HP_0008151 hasExactSynonym "Reduced prothrombin activity" @default.
- HP_0008151 hasExactSynonym "increased international normalised ratio" @default.
- HP_0008151 id "HP:0008151" @default.
- HP_0008151 type Class @default.
- HP_0008151 comment "The prothrombin time (PT) and the activated partial thromboplastin time (APTT) are the most requested tests to investigate patients with congenital or acquired coagulopathies and drug monitoring. They are defined as the time (seconds) needed to clot platelet-poor plasma upon addition of coagulation triggers, such as tissue factor in complex with phospholipids and calcium chloride (in the PT), or negatively charged phospholipids-activators and calcium chloride (in the APTT). They can hence be considered as global coagulation tests sensitive to deficiencies of many coagulation factors. In brief, they are both sensitive to factor X, V, II and fibrinogen, whereas the PT is only sensitive to factor VII deficiency and the APTT is sensitive to pre-kallikrein, high molecular weight kininogen (HMWK), factor XII, XI, IX and VIII deficiencies. Normal plasma in the PT clots approximately within 10-12 s upon triggering coagulation, and the normal reference range is (usually) narrow. PT results have been reported as clotting time, percentage activity, PT-ratio (patient-to-normal clotting time) and as international normalized ratio (INR). The INR scale has been devised to harmonize results stemming from different thromboplastins from patients on treatment with vitamin K antagonists. Some recommend abandoning the approach of using percentage activity to assess PR." @default.
- HP_0008151 isDefinedBy hp.owl @default.
- HP_0008151 label "Prolonged prothrombin time" @default.
- HP_0008151 subClassOf FYPO_0000001 @default.
- HP_0008151 subClassOf FYPO_0000300 @default.
- HP_0008151 subClassOf FYPO_0001985 @default.
- HP_0008151 subClassOf FYPO_0005447 @default.
- HP_0008151 subClassOf HP_0000001 @default.
- HP_0008151 subClassOf HP_0000118 @default.