Matches in Ubergraph for { <http://purl.obolibrary.org/obo/HP_0030066> ?p ?o ?g. }
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- HP_0030066 IAO_0000115 "A highly malignant embryonal tumor of infancy and young childhood characterized by neuroectodermal elements organized in distinctive multilayered rosettes. Ependymoblastomas are large lesions that occur in the supratentorial compartment, typically displaying a physical connection to the ventricular system." @default.
- HP_0030066 normalizedInformationContent "100" @default.
- HP_0030066 referenceCount "1" @default.
- HP_0030066 hasDbXref "MSH:D018242" @default.
- HP_0030066 hasDbXref "SNOMEDCT_US:21589007" @default.
- HP_0030066 hasDbXref "SNOMEDCT_US:715901002" @default.
- HP_0030066 hasDbXref "UMLS:C0700367" @default.
- HP_0030066 type Class @default.
- HP_0030066 comment "Ependymoblastoma is a rare tumor that occurs in infants and young children in the first two years of life. Both sexes are affected equally. Patients present with signs and symptoms of raised intracranial pressure and hydrocephalus. Focal neurological signs may be present in older children. On MRI, ependymoblastomas are large heterogeneously enhancing lesion with associated brain edema and mass effect. Ependymoblastomas are well-circumscribed lesions, with a distinct margin between tumor and normal brain, though focal microscopic extension and leptomeningeal invasion are common. Histologically, an ependymoblastoma is a primitive neuroectodermal tumor with tumor cell arranged in multilayered rosettes consisting of an outer rim of tumor cells merging with the surrounding undifferentiated neuroectodermal cells. The tumor cells are immunopositive for S100, vimentin, cytokeratin and GFAP, and show high mitotic activity." @default.
- HP_0030066 isDefinedBy hp.owl @default.
- HP_0030066 label "Ependymoblastoma" @default.
- HP_0030066 subClassOf HP_0000001 @default.
- HP_0030066 subClassOf HP_0000118 @default.
- HP_0030066 subClassOf HP_0002664 @default.
- HP_0030066 subClassOf HP_0011792 @default.
- HP_0030066 subClassOf HP_0030060 @default.
- HP_0030066 subClassOf HP_0030061 @default.
- HP_0030066 subClassOf HP_0030063 @default.
- HP_0030066 subClassOf HP_0030065 @default.
- HP_0030066 subClassOf HP_0030066 @default.
- HP_0030066 subClassOf HP_0030070 @default.
- HP_0030066 subClassOf UPHENO_0001001 @default.
- HP_0030066 category BiologicalEntity @default.
- HP_0030066 category DiseaseOrPhenotypicFeature @default.
- HP_0030066 category Entity @default.
- HP_0030066 category NamedThing @default.
- HP_0030066 category PathologicalEntityMixin @default.
- HP_0030066 category PhenotypicFeature @default.
- HP_0030066 category ThingWithTaxon @default.