Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C49456> ?p ?o ?g. }
- NCIT_C49456 IAO_0000115 "Human CDK4 wild-type allele is located within 12q14 and is approximately 4 kb in length. This allele, which encodes cyclin-dependent kinase 4 protein, is involved in the regulation of cell cycle progression from G1/S phase. Variant mutated alleles are associated with tumorigenesis for a variety of cancers." @default.
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- NCIT_C49456 NCIT_P101 "CDC2/CDKX Family" @default.
- NCIT_C49456 NCIT_P102 "U37022" @default.
- NCIT_C49456 NCIT_P106 "Gene or Genome" @default.
- NCIT_C49456 NCIT_P107 "CDK4 wt Allele" @default.
- NCIT_C49456 NCIT_P108 "CDK4 wt Allele" @default.
- NCIT_C49456 NCIT_P207 "C1707115" @default.
- NCIT_C49456 NCIT_P211 "G1/S transition of mitotic cell cycle" @default.
- NCIT_C49456 NCIT_P211 "cell proliferation" @default.
- NCIT_C49456 NCIT_P211 "cyclin-dependent protein kinase activity" @default.
- NCIT_C49456 NCIT_P211 "regulation of cell cycle" @default.
- NCIT_C49456 NCIT_P321 "1019" @default.
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- NCIT_C49456 NCIT_P96 "Cyclin-Dependent Kinase 4" @default.
- NCIT_C49456 NCIT_P98 "CDK4 was cloned for the study of hereditary melanoma. CDC37 and HSP90 enhance CDK4 stability. Cyclin-dependent kinase inhibitor-2 (p16) inhibits CDK4. Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. In addition, multiple polyadenylation sites of this gene have been reported." @default.
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- NCIT_C49456 hasExactSynonym "CDK4 wt Allele" @default.
- NCIT_C49456 hasExactSynonym "CMM3" @default.
- NCIT_C49456 hasExactSynonym "Cell Division Kinase 4 Gene" @default.
- NCIT_C49456 hasExactSynonym "Cyclin-Dependent Kinase 4 wt Allele" @default.
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