Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C51509> ?p ?o ?g. }
- NCIT_C51509 IAO_0000115 "Human LTA wild-type allele is located in the vicinity of 6p21.3 and is approximately 2 kb in length. This allele, which encodes lymphotoxin-alpha protein, is involved in the mediation of a large variety of inflammatory, immunostimulatory, and antiviral responses. In addition, the allele plays a role in secondary lymphoid organs during development and in apoptosis." @default.
- NCIT_C51509 NCIT_NHC0 "C51509" @default.
- NCIT_C51509 NCIT_P100 "153440" @default.
- NCIT_C51509 NCIT_P101 "TNF Family" @default.
- NCIT_C51509 NCIT_P102 "NM_000595" @default.
- NCIT_C51509 NCIT_P106 "Gene or Genome" @default.
- NCIT_C51509 NCIT_P108 "LTA wt Allele" @default.
- NCIT_C51509 NCIT_P207 "C1706393" @default.
- NCIT_C51509 NCIT_P211 "cell-cell signaling" @default.
- NCIT_C51509 NCIT_P211 "induction of apoptosis" @default.
- NCIT_C51509 NCIT_P211 "receptor binding" @default.
- NCIT_C51509 NCIT_P211 "signal transduction" @default.
- NCIT_C51509 NCIT_P321 "4049" @default.
- NCIT_C51509 NCIT_P366 "LTA_wt_Allele" @default.
- NCIT_C51509 NCIT_P96 "Tumor Necrosis Factor-Beta" @default.
- NCIT_C51509 NCIT_P98 "Human LTA Gene (TNF family) at 6p21.3 encodes TNF Beta, a glycoprotein cytokine of activated lymphocytes having cytotoxic and necrotic effects. Between C4 and HLA-B in the MHC region, TNFC resides just centromeric to TNFA, which is just centromeric to TNFB. These three similar genes lie about 200 kb from HLA-B. TNFC transcribes telomerically, TNFB and TNFA centromerically. MHC polymorphic microsatellites within a 12 kb region include TNFB. A putative immune response modulator similar to TNF Alpha, homotrimeric TNF Beta shares TNFR-1 and -2 receptors with TNF Alpha." @default.
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