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- CS202002013_233 cell_set_alias_assignee "Zizhen Yao" @default.
- CS202002013_233 cell_set_alias_citation "PMID:34616066" @default.
- CS202002013_233 cell_set_aligned_alias "Pvalb" @default.
- CS202002013_233 cell_set_label "RNAseq 048-057" @default.
- CS202002013_233 cell_set_preferred_alias "Pvalb-like" @default.
- CS202002013_233 node_metadata "{"cell_set_preferred_alias": "Pvalb-like", "original_label": "", "cell_set_label": "RNAseq 048-057", "cell_set_accession": "CS202002013_233", "cell_set_aligned_alias": "Pvalb", "cell_set_additional_aliases": "", "cell_set_alias_assignee": "Zizhen Yao", "cell_set_alias_citation": "PMID:34616066", "cell_set_structure": "primary motor cortex", "cell_set_ontology_tag": "UBERON:0001384", "species": "Mouse", "modality": "RNAseq", "taxonomy_id": "CCN202002013", "taxonomy_description": "Mouse MOp BICCN taxonomy using multiple RNA-Seq datasets ", "child_cell_set_accessions": "CS202002013_48|CS202002013_49|CS202002013_50|CS202002013_51|CS202002013_52|CS202002013_53|CS202002013_54|CS202002013_55|CS202002013_56|CS202002013_57", "cell_type_card": "Subclass", "cell_set_color": "#D93137"}" @default.
- CS202002013_233 PCL_0010051 "Subclass" @default.
- CS202002013_233 PCL_0010059 "CS202002013_233" @default.
- CS202002013_233 RO_0015003 CS202002013_168 @default.
- CS202002013_233 hasExactSynonym "Pvalb" @default.
- CS202002013_233 type B0d9efd465f2a0231a425873e16934a05 @default.
- CS202002013_233 type B12eaa0458233beccfcf0a76c5f12458b @default.
- CS202002013_233 type PCL_0010001 @default.
- CS202002013_233 type NamedIndividual @default.
- CS202002013_233 comment "Pvalb is: MGE-derived GABAergic subclass typically expressing Pvalb; includes basket and chandelier cells. In Mouse primary motor cortex (CCN202002013), Pvalb has 10 child types: Pvalb Gabrg1, Pvalb Egfem1, Pvalb Gpr149, Pvalb Kank4, Pvalb Calb1_1, Pvalb Calb1_2, Pvalb Reln, Pvalb Il1rapl2, Pvalb Vipr2_1 and Pvalb Vipr2_2. The minimal set of markers required to distinguish this cell type from other cell types in the primary motor cortex is Cntnap4 and Pvalb (F-beta = 0.867), based on the NS Forest method of marker gene selection. Pvalb cells represent 25.1% of all GABAergic cells collected in the snRNA-seq 10X v3 B dataset. Pvalb cells have an average of 5047 genes detected, which is 352 more than the average for all GABAergic cells (4695). The average normalized cortical depth of Pvalb cells is 0.563, compared to an average of 0.478 for all GABAergic cells. Pvalb cells have an average firing rate of 121.98 Hz, compared to 71.48 Hz for all GABAergic cells recorded. Other distinguishing features include an input resistance of 175.36 MOhms (262.76 MOhms in all GABAergic cells), and upstroke:downstroke ratio of 1.24 (1.91 for all GABAergic cells). The most distinguishing morpholgical features of Pvalb, as determined by reconstructions from Patch-seq data, are normalized cortical depth (0.48 vs. 0.4 average for all GABAergic cells), axon total length (16688.56 vs. 13796.3 microns for all GABAergic cells), dendrite total length (1892.01 vs. 2227.63 microns for all GABAergic cells), and stems (5.8 vs. 7.25 for all GABAergic cells)." @default.
- CS202002013_233 isDefinedBy cs202002013.owl @default.
- CS202002013_233 label "RNAseq 048-057 - CS202002013_233" @default.
- CS202002013_233 prefLabel "Pvalb-like" @default.